Phosphatidylinositol N-Acetylglucosaminyltransferase Subunit A

Preferred Label : Phosphatidylinositol N-Acetylglucosaminyltransferase Subunit A;

NCIt synonyms : GlcNAc-PI Synthesis Protein; Phosphatidylinositol Glycan Anchor Biosynthesis, Class A; EC 2.4.1.198; PIG-A; Phosphatidylinositol-Glycan Biosynthesis Class A Protein; PIGA;

NCIt definition : Phosphatidylinositol N-acetylglucosaminyltransferase subunit A (484 aa, 54 kDa) is encoded by the human PIGA gene. This protein is involved in the mediation of glycophosphoinositol anchor synthesis.;

Details

Origin ID

C95927;

UMLS CUI

C3272445;

OMIM relation
- Phosphatidylinositol glycan anchor biosynthesis class a protein [OMIM gene]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Enzyme [UMLS semantic type]
concept_is_in_subset
- CTRP Biomarker Terminology [NCIt concept]
- CTRP Molecular Genetic Biomarker Terminology [NCIt concept]
- CTRP Terminology [NCIt concept]
gene_encodes_gene_product
- Enzyme Gene [NCIt concept]
- Glycosyltransferase Gene [NCIt concept]
- PIGA Gene [NCIt concept]
- Transferase Gene [NCIt concept]
gene_product_has_associated_anatomy
- Endoplasmic Reticulum [NCIt concept]
gene_product_has_chemical_classification
- Transmembrane Protein [NCIt concept]
gene_product_has_structural_domain_or_motif
- Substrate Interaction Domain [NCIt concept]
gene_product_is_element_in_pathway
- Glycosylphosphatidylinositol-Anchor Biosynthesis Pathway [NCIt concept]
gene_product_malfunction_associated_with_disease
- Paroxysmal Nocturnal Hemoglobinuria [NCIt concept]
gene_product_plays_role_in_biological_process
- Carbohydrate Metabolic Process [NCIt concept]
- Glycosylation [NCIt concept]
- Protein Glycosylation [NCIt concept]

Keyword's position in hierarchy(ies) :

You can consult :

recommendations
documents concerning education
documents for patients