60 kDa Lysophospholipase

Preferred Label : 60 kDa Lysophospholipase;

NCIt synonyms : LysoLP; ASNase/PAF Acetylhydrolase; Lysophospholipase-Transacylase; L-Asparaginase/1-Alkyl-2-Acetylglycerophosphocholine Esterase; EC 3.1.1.5; ASPG; EC 3.5.1.1/EC 3.1.1.47;

NCIt definition : 60 kDa lysophospholipase (573 aa, 61 kDa) is encoded by the human ASPG gene. This protein is involved in transacylation activity and the metabolism of phospholipids and asparaginase.;

NCIt note : 60 kDa lysophospholipase has 2 domains, one with L-asparaginase (EC 3.5.1.1; L-asparagine amidohydrolase) activity and another with 1-alkyl-2-acetylglycerophosphocholine esterase (EC 3.1.1.47; platelet-activating factor acetylhydrolase; PAF acetylhydrolase) activity. (UniProt);

Details

Origin ID

C212180;

OMIM relation
- Asparaginase [OMIM gene]
gene_encodes_gene_product
- ASPG Gene [NCIt concept]
- Enzyme Gene [NCIt concept]
- Esterase Gene [NCIt concept]
- Hydrolase Gene [NCIt concept]
gene_product_has_associated_anatomy
- Cytosol [NCIt concept]
gene_product_has_biochemical_function
- Hydrolase [NCIt concept]
- Phospholipase [NCIt concept]
gene_product_has_structural_domain_or_motif
- Ankyrin Repeat [NCIt concept]
- Substrate Interaction Domain [NCIt concept]
gene_product_plays_role_in_biological_process
- Asparagine Metabolic Process [NCIt concept]
- Hydrolysis [NCIt concept]
- Phospholipid Metabolism [NCIt concept]

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