Tartrate-Resistant Acid Phosphatase Type 5

Preferred Label : Tartrate-Resistant Acid Phosphatase Type 5;

NCIt synonyms : TrATPase; Type 5 Acid Phosphatase; Tartrate-Resistant Acid Phosphatase Type 5a; TRACP-5a; Tartrate-Resistant Acid Phosphatase-5a; EC 3.1.3.2; Tartrate-Resistant Acid ATPase; TR-AP; ACP5;

NCIt definition : Tartrate-resistant acid phosphatase type 5 (325 aa, 37 kDa) is encoded by the human ACP5 gene. This protein plays a role in the mediation of phosphate group removal from sialoproteins.;

NCIt note : Tartrate-resistant acid phosphatase type 5a is predominantly secreted by macrophages and dendritic cells. (http://www.intermedico.com/userfiles/file/products/chemistry/IDS/trapwp.pdf);

Details

Origin ID

C99184;

UMLS CUI

C1566918;

Automatic exact mappings (from CISMeF team)
- Acid phosphatase bone isoenzyme (substance) [SNOMED CT concept]
- Acid phosphatase tartrate resistant [LOINC component]
- CD40 ligand [ORDO Gene]
- Cd40 ligand [OMIM gene]
- Periodic fever, familial, autosomal dominant [OMIM Phenotype]
- Phosphatase, acid, type 5, tartrate-resistant [OMIM gene]
- SCY1 like pseudokinase 1 [ORDO Gene]
- Tartrate-Resistant Acid Phosphatase [MeSH Descriptor]
- Tnf receptor-associated factor 2 [OMIM gene]
- Trapped [LOINC component]
- Trapping [MeSH concept]
- Triiodothyronine receptor auxiliary protein [OMIM Phenotype]
- Tudor domain-containing protein 7 [OMIM gene]
- acid phosphatase 5, tartrate resistant [ORDO Gene]
- transformation/transcription domain associated protein [ORDO Gene]
- trapping [IUPAC Term]
False automatic mappings
- Tumour necrosis factor receptor 1 associated periodic syndrome [ICD-11 Subcategory]
OMIM relation
- Phosphatase, acid, type 5, tartrate-resistant [OMIM gene]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Enzyme [UMLS semantic type]
UMLS correspondences (same concept)
- ACP5 protein, human [MeSH concept]
- ACP5 protein, human [MeSH Supplementary Concept]
concept_is_in_subset
- CTRP Biomarker Terminology [NCIt concept]
- CTRP Molecular Genetic Biomarker Terminology [NCIt concept]
- CTRP Terminology [NCIt concept]
gene_encodes_gene_product
- ACP5 Gene [NCIt concept]
- Enzyme Gene [NCIt concept]
- Esterase Gene [NCIt concept]
- Hydrolase Gene [NCIt concept]
- Phosphatase Family Gene [NCIt concept]
gene_product_expressed_in_tissue
- Dendritic Cell [NCIt concept]
- Macrophage [NCIt concept]
gene_product_has_associated_anatomy
- Lysosome [NCIt concept]
gene_product_has_biochemical_function
- Esterase [NCIt concept]
- Hydrolase [NCIt concept]
gene_product_has_chemical_classification
- Metalloprotein [NCIt concept]
gene_product_has_structural_domain_or_motif
- Substrate Interaction Domain [NCIt concept]
gene_product_is_element_in_pathway
- Lysosome Assembly Pathway [NCIt concept]
- Riboflavin Metabolism Pathway [NCIt concept]
gene_product_plays_role_in_biological_process
- Dephosphorylation [NCIt concept]
- Hydrolysis [NCIt concept]

Keyword's position in hierarchy(ies) :

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