Ras-Related Protein Rab-5A

Preferred Label : Ras-Related Protein Rab-5A;

NCIt synonyms : RAB5A; RAS-Associated Protein RAB5A; EC 3.6.5.2;

NCIt definition : Ras-related protein Rab-5A (215 aa, 24 kDa) is encoded by the human RAB5A gene. This protein plays a role in the regulation of endocytosis, exocytosis and autophagocytosis.;

Details

Origin ID

C171407;

UMLS CUI

C5400795;

Automatic exact mappings (from CISMeF team)
- RAB5A, member RAS oncogene family [HGNC gene]
- Ras-associated protein rab5a [OMIM gene]
OMIM relation
- Ras-associated protein rab5a [OMIM gene]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Enzyme [UMLS semantic type]
gene_encodes_gene_product
- Enzyme Gene [NCIt concept]
- Hydrolase Gene [NCIt concept]
- RAB5A Gene [NCIt concept]
- Signaling Pathway Gene [NCIt concept]
gene_product_has_associated_anatomy
- Autophagosome [NCIt concept]
- Exosome [NCIt concept]
- Membrane of the Endosome [NCIt concept]
- Plasma Membrane [NCIt concept]
gene_product_has_biochemical_function
- GTPase [NCIt concept]
gene_product_has_structural_domain_or_motif
- GTP Binding Domain [NCIt concept]
- Substrate Interaction Domain [NCIt concept]
gene_product_is_element_in_pathway
- Amoebiasis Pathway [NCIt concept]
- Endocytosis Pathway [NCIt concept]
- Epidermal Growth Factor Receptor Downstream Signaling Pathway [NCIt concept]
- Hepatocyte Growth Factor Receptor Signaling Pathway PID [NCIt concept]
- Internalization Pathway for Epidermal Growth Factor Receptor [NCIt concept]
- PDGFR-beta Signaling Pathway [NCIt concept]
- Phagocytosis Pathway [NCIt concept]
- Salmonella Pathway [NCIt concept]
- Vasopressin-Regulated Water Reabsorption Pathway [NCIt concept]
- p38-alpha and p38-beta Signaling Pathway [NCIt concept]
gene_product_plays_role_in_biological_process
- Autophagy [NCIt concept]
- Endocytotic Process [NCIt concept]
- Exocytosis [NCIt concept]
- GTP Binding [NCIt concept]
- Hydrolysis [NCIt concept]
- Intracellular Transport [NCIt concept]
- Signal Transduction [NCIt concept]

Keyword's position in hierarchy(ies) :

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