Alanine Aminotransferase 1

Preferred Label : Alanine Aminotransferase 1;

NCIt synonyms : GPT; Glutamic-Pyruvic Transaminase; Glutamic-Alanine Transaminase; Alanine Aminotransferase; ALT1; AAT1; GPT1; Glutamic--Pyruvic Transaminase 1; GPT 1; Glutamic-Pyruvate Transaminase; Glutamic--Alanine Transaminase 1; Glutamate Pyruvate Transaminase 1; EC 2.6.1.2; Glutamic-Pyruvic Transaminase 1; Glutamic-Alanine Transaminase 1;

NCIt definition : Alanine aminotransferase 1 (496 aa, 55 kDa) is encoded by the human GPT gene. This protein plays a role in both amino acid metabolism and pyruvate synthesis.;

NCIt note : Protein_Plays_Role_In_Biological_Process: Nitrogen Metabolism, Transamination;

Details

Origin ID

C38507;

UMLS CUI

C3887708;

Automatic exact mappings (from CISMeF team)
- 1-(2'-deoxy-beta-D-glucopyranosyl)thymine [MeSH Supplementary Concept]
- Aortic aneurysm, familial thoracic 1 [OMIM Phenotype]
- Cilia- and flagella-associated protein 91 [OMIM gene]
- D-Alanine transaminase [MeSH Descriptor]
- GPT [MedDRA LLT]
- Glutamate pyruvate transaminase [OMIM gene]
- L-alanine:2-oxoglutarate aminotransferase activity [GO term]
- alanine aminotransferase [COVID-19 Thesaurus concept]
- alanine aminotransferase [Artificial nutrition thesaurus concept]
- dolichyl-phosphate N-acetylglucosaminephosphotransferase 1 [ORDO Gene]
- glutamic--pyruvic transaminase [HGNC gene]
- glycopeptide T1 [MeSH Supplementary Concept]
- transaminase [Artificial nutrition thesaurus concept]
Currated CISMeF NLP mapping
- Alanine amino-transferase [ICHI extension code]
- Alanine aminotransferase [LOINC component]
- Alanine aminotransferase [MedDRA Preferred Term]
- Alanine aminotransferase (substance) [SNOMED CT concept]
- Glutamic-pyruvate transaminase [MedDRA LLT]
- alanine amino-transferase [EMDN type]
- alanine aminotransferase [medical devices type]
- alanine aminotransferase [SNOMED Notion]
- alanine transaminase [MeSH Descriptor]
- alanine transaminase [MeSH concept]
OMIM relation
- Glutamate pyruvate transaminase [OMIM gene]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Enzyme [UMLS semantic type]
gene_encodes_gene_product
- Enzyme Gene [NCIt concept]
- GPT Gene [NCIt concept]
- Transferase Gene [NCIt concept]
gene_product_has_structural_domain_or_motif
- Substrate Interaction Domain [NCIt concept]
gene_product_is_element_in_pathway
- Alanine, Aspartate and Glutamate Metabolism Pathway [NCIt concept]
- SARS Coronavirus Protease Pathway [NCIt concept]
gene_product_plays_role_in_biological_process
- Gluconeogenic Process [NCIt concept]
- Protein Metabolism Process [NCIt concept]

Keyword's position in hierarchy(ies) :

Main resources

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