Dipeptidase 3 - CISMeF

Preferred Label : Dipeptidase 3;

NCIt synonyms : Membrane-Bound Dipeptidase 3; Testis Secretory Sperm-Binding Protein Li 211a; DPEP3; EC 3.4.13.19;

NCIt definition : Dipeptidase 3 (488 aa, 54 kDa) is encoded by the human DPEP3 gene. This protein is involved in the cleavage of cystinyl-bis-glycine.;

NCIt note : Dipeptidase 3 is associated with the plasma membrane via a GPI-anchor attached at serine-463. The dipeptidase 3 zymogen is cleaved N-terminally to release the signal peptide and then C-terminally to produce the active disulfide-linked 2 chain form. (UniProt);

NCI Metathesaurus CUI : CL1399974;

Details

Origin ID

C181964;

UMLS CUI

C5226717;

Automatic exact mappings (from CISMeF team)
- Dipeptidase 3 [OMIM gene]
- dipeptidase 3 [HGNC gene]
OMIM relation
- Dipeptidase 3 [OMIM gene]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Enzyme [UMLS semantic type]
UMLS correspondences (same concept)
- DPEP3 protein, human [MeSH Supplementary Concept]
concept_is_in_subset
- CTRP Biomarker Terminology [NCIt concept]
- CTRP Molecular Genetic Biomarker Terminology [NCIt concept]
- CTRP Terminology [NCIt concept]
gene_encodes_gene_product
- DPEP3 Gene [NCIt concept]
- Enzyme Gene [NCIt concept]
- Hydrolase Gene [NCIt concept]
- Metallopeptidase Gene [NCIt concept]
- Peptidase Gene [NCIt concept]
gene_product_has_associated_anatomy
- Plasma Membrane [NCIt concept]
gene_product_has_chemical_classification
- Metalloprotein [NCIt concept]
gene_product_has_structural_domain_or_motif
- Protease Domain [NCIt concept]
- Substrate Interaction Domain [NCIt concept]
gene_product_is_biomarker_type
- Metastasis and Aggressiveness Marker [NCIt concept]
gene_product_plays_role_in_biological_process
- Catabolic Process [NCIt concept]
- Hydrolysis [NCIt concept]
- Metal Ion Binding [NCIt concept]
- Peptide Metabolism [NCIt concept]
- Proteolysis [NCIt concept]
is_target
- Tamrintamab Pamozirine [NCIt concept]

Keyword's position in hierarchy(ies) :

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