Preferred Label : Threonine-tRNA Ligase 1, Cytoplasmic;
NCIt synonyms : Threonine-tRNA Ligase, Cytoplasmic; Threonyl-tRNA Synthetase, Cytoplasmic; Threonine tRNA Ligase 1, Cytoplasmic; Threonyl-tRNA Synthetase 1; Threonine--tRNA Ligase, Cytoplasmic; ThrRS; EC 6.1.1.3; Threonine tRNA Ligase, Cytoplasmic; TARS1; Threonine--tRNA Ligase 1, Cytoplasmic;
NCIt related terms : TRS; Threonyl-tRNA Synthetase; PL-7 ANTIGEN;
NCIt definition : Threonine-tRNA ligase 1, cytoplasmic (723 aa, 83 kDa) is encoded by the human TARS1
gene. This protein is involved in tRNA aminoacylation for protein translation.;
Alternative definition : CDISC: An antigen encoded by the TARS1 gene that regulates threonyl-transfer RNA synthesis
(attaches threonine to tRNA). It can be considered as an autoantigen and is commonly
associated with the autoimmune diseases anti-synthetase syndrome, polymyositis and
dermatomyositis.;
NCI Metathesaurus CUI : CL1407184;
Origin ID : C173323;
UMLS CUI : C5400884;
Automatic exact mappings (from CISMeF team)
- OMIM relation
- Semantic type(s)
- concept_is_in_subset
- gene_encodes_gene_product
- gene_product_has_associated_anatomy
- gene_product_has_chemical_classification
- gene_product_has_structural_domain_or_motif
- gene_product_is_element_in_pathway
- gene_product_plays_role_in_biological_process
