Sphingomyelin Phosphodiesterase 3

Preferred Label : Sphingomyelin Phosphodiesterase 3;

NCIt synonyms : EC 3.1.4.12; nSMase2; nSMase-2; Neutral Sphingomyelinase II; SMPD3;

NCIt definition : Sphingomyelin phosphodiesterase 3 (655 aa, 71 kDa) is encoded by the human SMPD3 gene. This protein plays a role in ceramide biosynthesis.;

Details

Origin ID

C105032;

UMLS CUI

C3539582;

OMIM relation
- Sphingomyelin phosphodiesterase 3, neutral membrane [OMIM gene]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Enzyme [UMLS semantic type]
concept_is_in_subset
- CTRP Biomarker Terminology [NCIt concept]
- CTRP Molecular Genetic Biomarker Terminology [NCIt concept]
- CTRP Terminology [NCIt concept]
gene_encodes_gene_product
- Enzyme Gene [NCIt concept]
- Esterase Gene [NCIt concept]
- Hydrolase Gene [NCIt concept]
- SMPD3 Gene [NCIt concept]
gene_product_has_associated_anatomy
- Membrane of the Golgi Apparatus [NCIt concept]
gene_product_has_biochemical_function
- Hydrolase [NCIt concept]
gene_product_has_structural_domain_or_motif
- Substrate Interaction Domain [NCIt concept]
gene_product_is_element_in_pathway
- Ceramide Signaling Pathway PID [NCIt concept]
- FAS Signaling Pathway PID [NCIt concept]
- Sphingolipid Metabolism Pathway [NCIt concept]
gene_product_plays_role_in_biological_process
- Hydrolysis [NCIt concept]
- Phospholipid Metabolism [NCIt concept]
- Signal Transduction [NCIt concept]

Keyword's position in hierarchy(ies) :

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