Tryptophan 5-Hydroxylase 1

Preferred Label : Tryptophan 5-Hydroxylase 1;

NCIt synonyms : Tryptophan 5-Monooxygenase; EC 1.14.16.4; Tryptophan 5-Monooxygenase 1; TPH1;

NCIt definition : Tryptophan 5-hydroxylase 1 (444 aa, 51 kDa) is encoded by the human TPH1 gene. This protein plays a role in the metabolism of tryptophan.;

Details

Origin ID

C105873;

UMLS CUI

C1566598;

Automatic exact mappings (from CISMeF team)
- Tryptophan 5-monooxygenase (substance) [SNOMED CT concept]
- Tryptophan hydroxylase 1 [OMIM gene]
- tryptophan 5-monooxygenase [SNOMED Notion]
- tryptophan hydroxylase [MeSH Descriptor]
- tryptophan hydroxylase 1 [HGNC gene]
- tryptophan hydroxylase 2 [HGNC gene]
OMIM relation
- Tryptophan hydroxylase 1 [OMIM gene]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Enzyme [UMLS semantic type]
UMLS correspondences (same concept)
- TPH1 protein, human [MeSH Supplementary Concept]
- TPH1 protein, human [MeSH concept]
concept_is_in_subset
- CTRP Biomarker Terminology [NCIt concept]
- CTRP Molecular Genetic Biomarker Terminology [NCIt concept]
- CTRP Terminology [NCIt concept]
gene_encodes_gene_product
- Enzyme Gene [NCIt concept]
- Oxidoreductase Gene [NCIt concept]
- TPH1 Gene [NCIt concept]
gene_product_has_associated_anatomy
- Cytosol [NCIt concept]
gene_product_has_structural_domain_or_motif
- Substrate Interaction Domain [NCIt concept]
gene_product_is_element_in_pathway
- Tryptophan Metabolism Pathway [NCIt concept]
gene_product_plays_role_in_biological_process
- Oxidation [NCIt concept]
- Oxidation/Reduction [NCIt concept]
- Serotonin Production [NCIt concept]
is_target
- Telotristat Etiprate [NCIt concept]

Keyword's position in hierarchy(ies) :

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