OTU Domain-Containing Protein 5

Preferred Label : OTU Domain-Containing Protein 5;

NCIt synonyms : DUBA; EC 3.4.19.12; Deubiquinating Enzyme A; Deubiquitinating Enzyme A; OTUD5;

NCIt definition : OTU domain-containing protein 5 (571 aa, 61 kDa) is encoded by the human OTUD5 gene. This protein plays a role in protein deubiquitination that modulates inate immunity.;

Details

Origin ID

C124954;

UMLS CUI

C2000427;

Automatic exact mappings (from CISMeF team)
- Deubiquitinating Enzymes [MeSH concept]
- Deubiquitinating Enzymes [MeSH Descriptor]
- Otu domain-containing protein 5 [OMIM gene]
- cysteine-type deubiquitinase activity [GO term]
- ubiquitin isopeptidase [MeSH Supplementary Concept]
OMIM relation
- Otu domain-containing protein 5 [OMIM gene]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Enzyme [UMLS semantic type]
UMLS correspondences (same concept)
- OTUD5 protein, human [MeSH Supplementary Concept]
- OTUD5 protein, human [MeSH concept]
gene_encodes_gene_product
- Cysteine Peptidase Gene [NCIt concept]
- Enzyme Gene [NCIt concept]
- Hydrolase Gene [NCIt concept]
- OTUD5 Gene [NCIt concept]
- Peptidase Gene [NCIt concept]
gene_product_has_associated_anatomy
- Cytoplasm [NCIt concept]
gene_product_has_biochemical_function
- Deubiquitinating Enzyme [NCIt concept]
gene_product_has_structural_domain_or_motif
- Protease Domain [NCIt concept]
- Substrate Interaction Domain [NCIt concept]
gene_product_is_element_in_pathway
- RIG-I-Like Receptor Signaling Pathway [NCIt concept]
gene_product_plays_role_in_biological_process
- Deubiquitination [NCIt concept]
- Hydrolysis [NCIt concept]
- Immune System Process [NCIt concept]
- Proteolysis [NCIt concept]
- Regulation of Proteolysis [NCIt concept]

Keyword's position in hierarchy(ies) :

You can consult :

recommendations
documents concerning education
documents for patients