ubiquitin isopeptidase

Preferred Label : ubiquitin isopeptidase;

MeSH note : has both isopeptidase & peptidase activities in vitro; cleaves both peptide-linked and isopeptide-linked ubiquitin moieties from substrates; RefSeq NM_003481 (USP5, human); NM_005154 (USP8, human); NM_019729 (Usp8, mouse);

CISMeF synonym : USP5 protein, human; isopeptidase T, xenopus laevis;

MeSH synonym : de-ubiquitinase; de-ubiquitinating enzyme; ubiquitin-specific isopeptidase;

MeSH hyponym : ubiquitin specific protease 5 protein, human; Ubiquitin carboxyl-terminal hydrolase 5 protein, human; Ubiquitin isopeptidase T protein, human; 100 kDa isopeptidase protein, human; isopeptidase T protein, human;

Registry Number MeSH : EC 3.4.99.-;

Is substance : O;

Details

Origin ID

C091939;

UMLS CUI

C0294105;

Automatic exact mappings (from CISMeF team)
- Deubiquitinating Enzyme [NCIt concept]
- OTU Domain-Containing Protein 5 [NCIt concept]
- cysteine-type deubiquitinase activity [GO term]
MeSH indexing information
- oncogene proteins [MeSH Descriptor]
- ubiquitins [MeSH Descriptor]
MeSH term(s) associated for indexing
- endopeptidases [MeSH Descriptor]
Record concept(s)
- USP5 protein, human [MeSH concept]
- isopeptidase T, xenopus laevis [MeSH concept]
- ubiquitin isopeptidase [MeSH concept]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Enzyme [UMLS semantic type]

Keyword's position in hierarchy(ies) :

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