UDP-Glucuronosyltransferase 2B17

Preferred Label : UDP-Glucuronosyltransferase 2B17;

NCIt synonyms : UGT2B17; UDP-Glucuronyltransferase, Family 2, Beta-17; UDPGT 2B17; UDP Glycosyltransferase 2 Family, Polypeptide B17; EC 2.4.1.17; UDP Glycosyltransferase 2 Family, Member B17; C19-Steroid-Specific UDP-Glucuronosyltransferase; C19-Steroid-Specific UDPGT;

NCIt definition : UDP-glucuronosyltransferase 2B17 (530 aa, 61 kDa) is encoded by the human UGT2B17 gene. This protein plays a role in the metabolism of steroids and xenobiotics.;

NCIt note : Substrates for UDP-glucoronosyltransferase 2B17 include eugenol, 4-methylumbelliferone, dihydrotestosterone (DHT), androstane-3-alpha,17-beta-diol (3-alpha-diol), testosterone and androsterone. (UniProt);

Details

Origin ID

C105425;

UMLS CUI

C1569087;

OMIM relation
- Uridine diphosphate glycosyltransferase 2 family, member b17 [OMIM gene]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Enzyme [UMLS semantic type]
UMLS correspondences (same concept)
- UGT2B17 protein, human [MeSH Supplementary Concept]
- UGT2B17 protein, human [MeSH concept]
concept_is_in_subset
- CTRP Biomarker Terminology [NCIt concept]
- CTRP Molecular Genetic Biomarker Terminology [NCIt concept]
- CTRP Terminology [NCIt concept]
gene_encodes_gene_product
- Enzyme Gene [NCIt concept]
- Glycosyltransferase Gene [NCIt concept]
- Transferase Gene [NCIt concept]
- UGT2B17 Gene [NCIt concept]
gene_product_has_associated_anatomy
- Membrane of the Endoplasmic Reticulum [NCIt concept]
gene_product_has_structural_domain_or_motif
- Substrate Interaction Domain [NCIt concept]
gene_product_is_element_in_pathway
- Ascorbate and Aldarate Metabolism Pathway [NCIt concept]
- Drug Metabolism by Cytochrome P450 Pathway [NCIt concept]
- Drug Metabolism by Non-CYP450 Enzymes Pathway [NCIt concept]
- Metabolism of Xenobiotics by Cytochrome P450 Pathway [NCIt concept]
- Pentose and Glucuronate Interconversions Pathway [NCIt concept]
- Porphyrin and Chlorophyll Metabolism Pathway [NCIt concept]
- Retinol Metabolism Pathway [NCIt concept]
- Starch and Sucrose Metabolism Pathway [NCIt concept]
- Steroid Hormone Biosynthesis Pathway [NCIt concept]
gene_product_plays_role_in_biological_process
- Carbohydrate Metabolic Process [NCIt concept]
- Glycosylation [NCIt concept]
- Steroid Metabolic Process [NCIt concept]
- Xenobiotic Metabolism [NCIt concept]

Keyword's position in hierarchy(ies) :

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