DNA Ligase 1 - CISMeF

Preferred Label : DNA Ligase 1;

NCIt synonyms : EC 6.5.1.1; Polydeoxyribonucleotide Synthase [ATP] 1; DNA Ligase I; LIG1;

NCIt definition : DNA ligase 1 (919 aa, 102 kDa) is encoded by the human LIG1 gene. This protein plays a role in DNA replication and repair of nicks in double stranded DNA.;

Details

Origin ID

C91274;

UMLS CUI

C4307963;

Automatic exact mappings (from CISMeF team)
- Cdc17 protein, S pombe [MeSH Supplementary Concept]
- DNA Ligase ATP [MeSH Descriptor]
- DNA ligase 1 [HGNC gene]
- Isoleucine-tRNA ligase [MeSH Descriptor]
- Leucine-rich repeats- and immunoglobulin-like domains-containing protein 1 [OMIM gene]
- Ligase I, dna, atp-dependent [OMIM gene]
- formyltetrahydrofolate dehydrogenase [MeSH Supplementary Concept]
- tilS protein, E coli [MeSH Supplementary Concept]
OMIM relation
- Ligase I, dna, atp-dependent [OMIM gene]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Enzyme [UMLS semantic type]
UMLS correspondences (same concept)
- DNA ligase I [MeSH concept]
- LIG1 protein, human [MeSH Supplementary Concept]
concept_is_in_subset
- CTRP Biomarker Terminology [NCIt concept]
- CTRP Molecular Genetic Biomarker Terminology [NCIt concept]
- CTRP Terminology [NCIt concept]
gene_encodes_gene_product
- Enzyme Gene [NCIt concept]
- LIG1 Gene [NCIt concept]
- Ligase Gene [NCIt concept]
gene_product_has_organism_source
- Human [NCIt concept]
gene_product_has_structural_domain_or_motif
- Substrate Interaction Domain [NCIt concept]
gene_product_plays_role_in_biological_process
- DNA Recombination Process [NCIt concept]
- DNA Replication [NCIt concept]
- Nucleotide Excision Repair [NCIt concept]

Keyword's position in hierarchy(ies) :

You can consult :

recommendations
documents concerning education
documents for patients