DNA Ligase ATP

Preferred Label : DNA Ligase ATP;

MeSH definition : ATP-dependent cellular enzyme which catalyzes DNA replication, repair and recombination through formation of internucleotide ester bonds between phosphate and deoxyribose moieties. Vertebrate cells encode three well-characterized DNA ligases, DNA ligase I, III and IV, all of which are related in structure and sequence. DNA ligases either require ATP or NAD. However, archaebacterial, viral, and some eubacterial DNA ligases are ATP-dependent.;

MeSH synonym : ATP, DNA Ligase; Ligase ATP, DNA; ATP-Dependent DNA Ligases; DNA Ligases, ATP Dependent; Ligases, ATP-Dependent DNA; ATP, Polydeoxyribonucleotide Synthase; Synthase ATP, Polydeoxyribonucleotide; Polydeoxyribonucleotide Synthase ATP; DNA Ligases, ATP-Dependent; ATP-Dependent DNA Ligase; ATP Dependent DNA Ligase; DNA Ligase, ATP-Dependent; Ligase, ATP-Dependent DNA;

DeCS synonym : DNA Ligase IIIalpha; DNA Ligase I; DNA Ligase IV; DNA Ligase III; LIGIIIalpha Protein;

MeSH hyponym : Ligase I, DNA; IIIalpha, DNA Ligase; Ligase IIIalpha, DNA; LIGIIIalpha Protein; Ligase IV, DNA; Ligase III, DNA; DNA Ligase II; Ligase II, DNA;

MeSH Related Number : EC 6.5.1.1;

Registry Number MeSH : EC 6.5.1.1;

UNII : EC 6.5.1.1;

Details

Origin ID

D000072481;

UMLS CUI

C4277692;

Allowable qualifiers
- administration and dosage [MeSH Qualifier]
- adverse effects [MeSH Qualifier]
- analysis [MeSH Qualifier]
- antagonists and inhibitors [MeSH Qualifier]
- biosynthesis [MeSH Qualifier]
- blood [MeSH Qualifier]
- cerebrospinal fluid [MeSH Qualifier]
- chemical synthesis [MeSH Qualifier]
- chemistry [MeSH Qualifier]
- classification [MeSH Qualifier]
- contraindications [MeSH Qualifier]
- deficiency [MeSH Qualifier]
- drug effects [MeSH Qualifier]
- economics [MeSH Qualifier]
- genetics [MeSH Qualifier]
- history [MeSH Qualifier]
- immunology [MeSH Qualifier]
- isolation and purification [MeSH Qualifier]
- metabolism [MeSH Qualifier]
- pharmacokinetics [MeSH Qualifier]
- pharmacology [MeSH Qualifier]
- physiology [MeSH Qualifier]
- poisoning [MeSH Qualifier]
- radiation effects [MeSH Qualifier]
- standards [MeSH Qualifier]
- supply and distribution [MeSH Qualifier]
- therapeutic use [MeSH Qualifier]
- toxicity [MeSH Qualifier]
- ultrastructure [MeSH Qualifier]
- urine [MeSH Qualifier]
Automatic exact mappings (from CISMeF team)
- DNA Ligase 1 [NCIt concept]
- DNA Ligase 3 [NCIt concept]
- DNA Ligase 4 [NCIt concept]
- LIG4 wt Allele [NCIt concept]
- Ligase I, dna, atp-dependent [OMIM gene]
- Ligase III, dna, atp-dependent [OMIM gene]
- Ligase iv, dna, atp-dependent [OMIM gene]
- polydeoxyribonucleotide synthase (atp) [SNOMED Notion]
Currated CISMeF NLP mapping
- Polydeoxyribonucleotide synthase (adenosine triphosphate) (substance) [SNOMED CT concept]
Record concept(s)
- DNA Ligase ATP [MeSH concept]
- DNA Ligase III [MeSH concept]
- DNA ligase I [MeSH concept]
- DNA ligase IIIalpha [MeSH concept]
- DNA ligase IV [MeSH concept]
Related MeSH Supplementary Concept(s)
- CDC9 protein, S cerevisiae [MeSH Supplementary Concept]
- DNA ligase III alpha protein, Xenopus [MeSH Supplementary Concept]
- DNL4 protein, S cerevisiae [MeSH Supplementary Concept]
- LIG1 protein, human [MeSH Supplementary Concept]
- LIG3 protein, human [MeSH Supplementary Concept]
- LIG4 protein, human [MeSH Supplementary Concept]
- Lig1 protein, mouse [MeSH Supplementary Concept]
- Lig1 protein, rat [MeSH Supplementary Concept]
- Lig3 protein, mouse [MeSH Supplementary Concept]
- Lig3 protein, rat [MeSH Supplementary Concept]
- Lig4 protein, mouse [MeSH Supplementary Concept]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Enzyme [UMLS semantic type]
UMLS correspondences (same concept)
- Polydeoxyribonucleotide synthase (adenosine triphosphate) (substance) [SNOMED CT concept]

Keyword's position in hierarchy(ies) :

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