Palmitoyltransferase ZDHHC8

Preferred Label : Palmitoyltransferase ZDHHC8;

NCIt synonyms : Zinc Finger DHHC Domain-Containing Protein 8; Zinc Finger DHHC-Type Palmitoyltransferase 8; Zinc Finger DHHC-Type Containing 8; Zinc Finger Protein 378; ZDHHC8; EC 2.3.1.225; Membrane-Associated DHHC8 Zinc Finger Protein; DHHC-8;

NCIt definition : Palmitoyltransferase ZDHHC8 (765 aa, 81 kDa) is encoded by the human ZDHHC8 gene. This protein plays a role in protein palmitoylation and membrane localization.;

NCIt note : Palmitoyltransferase ZDHHC8 catalyzes the transfer of palmitoyl groups to cysteines in protein substrates including ABCA1 and DRD2. (UniProt);

Details

Origin ID

C185088;

UMLS CUI

C1454604;

Automatic exact mappings (from CISMeF team)
- Zinc finger dhhc domain-containing protein 8 [OMIM gene]
- zinc finger DHHC-type palmitoyltransferase 8 [HGNC gene]
OMIM relation
- Zinc finger dhhc domain-containing protein 8 [OMIM gene]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Enzyme [UMLS semantic type]
UMLS correspondences (same concept)
- ZDHHC8 protein, human [MeSH Supplementary Concept]
- ZDHHC8 protein, human [MeSH concept]
concept_is_in_subset
- NCIt COVID-19 Clinical Terminology [NCIt concept]
- NCIt COVID-19 Terminology [NCIt concept]
gene_encodes_gene_product
- Enzyme Gene [NCIt concept]
- Transferase Gene [NCIt concept]
- ZDHHC8 Gene [NCIt concept]
gene_product_expressed_in_tissue
- All Sites [NCIt concept]
gene_product_has_associated_anatomy
- Membrane of the Golgi Apparatus [NCIt concept]
- Mitochondrial Membrane [NCIt concept]
gene_product_has_chemical_classification
- Transmembrane Protein [NCIt concept]
gene_product_has_structural_domain_or_motif
- Metal Binding Site [NCIt concept]
- Substrate Interaction Domain [NCIt concept]
- Transmembrane Domain [NCIt concept]
gene_product_plays_role_in_biological_process
- Lipid Metabolic Process [NCIt concept]
- Metal Ion Binding [NCIt concept]
- Post-Translational Modification [NCIt concept]

Keyword's position in hierarchy(ies) :

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