Nucleotide Triphosphate Diphosphatase NUDT15

Preferred Label : Nucleotide Triphosphate Diphosphatase NUDT15;

NCIt synonyms : MTH2; Nucleoside Diphosphate-Linked to Another Moiety X Hydrolase 15; MutT Homolog 2; Nucleoside Diphosphate-Linked Moiety X Motif 15; NUDT15; Nudix Hydrolase 15; EC 3.6.1.9; Nudix Motif 15;

NCIt definition : Nucleotide triphosphate diphosphatase NUDT15 (164 aa, 19 kDa) is encoded by the human NUDT15 gene. This protein is involved in the hydrolysis of dGTP, dTTP, dCTP and the metabolism of thiopurine-type toxins and prodrugs.;

NCI Metathesaurus CUI : CL1670468;

Details

Origin ID

C202283;

UMLS CUI

C2743282;

OMIM relation
- Nudix hydrolase 15 [OMIM gene]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Enzyme [UMLS semantic type]
UMLS correspondences (same concept)
- NUDT15 protein, human [MeSH Supplementary Concept]
- NUDT15 protein, human [MeSH concept]
gene_encodes_gene_product
- Enzyme Gene [NCIt concept]
- Hydrolase Gene [NCIt concept]
- NUDT15 Gene [NCIt concept]
gene_product_has_associated_anatomy
- Cytoplasm [NCIt concept]
gene_product_has_structural_domain_or_motif
- Substrate Interaction Domain [NCIt concept]
gene_product_plays_role_in_biological_process
- Detoxification [NCIt concept]
- Hydrolysis [NCIt concept]
- Nucleotide Metabolic Process [NCIt concept]

Keyword's position in hierarchy(ies) :

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