Poly [ADP-Ribose] Polymerase Tankyrase-1

Preferred Label : Poly [ADP-Ribose] Polymerase Tankyrase-1;

NCIt synonyms : PARP Homolog; TNKS; TRF1-Interacting Ankyrin-Related ADP-Ribose Polymerase; Telomeric Poly-(ADP-Ribose)-Polymerase; Telomeric Poly (ADP-Ribose) Polymerase; EC 2.4.2.30; TANK1; Tankyrase I; Tankyrase; ADP-Ribosyltransferase Diphtheria Toxin-Like 5; Poly [ADP-Ribose] Polymerase 5A; TNKS-1; ARTD5; TRF1-Interacting Ankyrin-Related ADP-Ribose Polymerase 1; Tankyrase 1;

NCIt related terms : Tankyrase-1;

NCIt definition : Poly [ADP-ribose] polymerase tankyrase-1 (1327 aa, 142 kDa) is encoded by the human TNKS gene. This protein plays a role in poly-ADP-ribosylation of protein substrates.;

Details

Origin ID

C20125;

UMLS CUI

C1504783;

Currated CISMeF NLP mapping
- tankyrases [MeSH Descriptor]
- tankyrases [MeSH concept]
OMIM relation
- Tankyrase [OMIM gene]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Enzyme [UMLS semantic type]
UMLS correspondences (same concept)
- TNKS protein, human [MeSH Supplementary Concept]
- TNKS protein, human [MeSH concept]
- tankyrases [MeSH Descriptor]
concept_is_in_subset
- CTRP Biomarker Terminology [NCIt concept]
- CTRP Molecular Genetic Biomarker Terminology [NCIt concept]
- CTRP Terminology [NCIt concept]
gene_encodes_gene_product
- Enzyme Gene [NCIt concept]
- Glycosyltransferase Gene [NCIt concept]
- TNKS Gene [NCIt concept]
- Transferase Gene [NCIt concept]
gene_product_has_biochemical_function
- Ubiquitination Regulation Protein [NCIt concept]
gene_product_has_structural_domain_or_motif
- Ankyrin Repeat [NCIt concept]
- SAM Domain [NCIt concept]
- Substrate Interaction Domain [NCIt concept]
gene_product_is_element_in_pathway
- Telomerase Regulation Pathway [NCIt concept]
- Telomere Pathway [NCIt concept]
gene_product_plays_role_in_biological_process
- Carbohydrate Metabolic Process [NCIt concept]
- Glycosylation [NCIt concept]
- Poly-ADP-Ribosylation [NCIt concept]
- Spindle Assembly Interaction [NCIt concept]
- Telomere Maintenance [NCIt concept]
is_target
- Basroparib [NCIt concept]
- Nesuparib [NCIt concept]

Keyword's position in hierarchy(ies) :

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