" /> Poly [ADP-Ribose] Polymerase Protein Family - CISMeF





Preferred Label : Poly [ADP-Ribose] Polymerase Protein Family;

NCIt synonyms : PARP; NAD( ) ADP-Ribosyltransferase; PARP Family; Poly(ADP-Ribose)Polymerase; Poly [ADP-Ribose] Polymerase Family; Poly(Adenosine Diphosphate Ribose) Polymerase; Poly [ADP-Ribose] Polymerase; Poly (ADP-Ribose) Polymerase;

NCIt definition : A family of glycosyltransferases that catalyzes both the transfer of an adenosine diphosphate (ADP)-ribosyl group of oxidized nicotinamide adenine dinucleotide (NAD( )) to an acceptor carboxyl group in protein substrates and continued transfer of ADP-ribosyl groups to the 2'-position of the terminal adenosine moiety, building up a polymer with an average chain length of 20-30 units. This process (poly-ADP-ribosylation) is involved in a number of cellular processes, including DNA repair, genomic stability and the regulation of programmed cell death.;

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Position du mot-clé dans l'(les) arborescence(s) : arborescence

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30/07/2025


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