Poly [ADP-Ribose] Polymerase 1 p85

Preferred Label : Poly [ADP-Ribose] Polymerase 1 p85;

NCIt synonyms : PARP p85; ARTD1 p85; PARP1 p85; Poly(ADP Ribose) Polymerase p85; ADP-Ribosyltransferase Diphtheria Toxin-Like 1 p85; Poly [ADP-Ribose] Polymerase p85; NAD( ) ADP-Ribosyltransferase 1 p85; Poly[ADP-Ribose] Synthase 1 p85; ADPRT 1 p85; Poly(ADP Ribose) Polymerase 1 p85;

NCIt definition : Poly [ADP-ribose] polymerase 1 p85 (800 aa, 89 kDa) is encoded by the human PARP1 gene. This protein is released from the full length poly [ADP-ribose] polymerase 1 protein by caspase-3 cleavage and is involved in DNA repair.;

NCIt note : The presence of poly [ADP-ribose] polymerase 1 p85 can be assayed as a marker for apoptosis.;

Details

Origin ID

C104102;

UMLS CUI

C3641724;

OMIM relation
- Poly(adp-ribose) polymerase 1 [OMIM gene]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Biologically Active Substance [UMLS semantic type]
concept_is_in_subset
- CTRP Biomarker Terminology [NCIt concept]
- CTRP Molecular Genetic Biomarker Terminology [NCIt concept]
- CTRP Terminology [NCIt concept]
gene_encodes_gene_product
- DNA Repair Gene [NCIt concept]
- Enzyme Gene [NCIt concept]
- Glycosyltransferase Gene [NCIt concept]
- PARP1 Gene [NCIt concept]
- Transferase Gene [NCIt concept]
gene_product_has_structural_domain_or_motif
- Substrate Interaction Domain [NCIt concept]
gene_product_plays_role_in_biological_process
- Carbohydrate Metabolic Process [NCIt concept]
- DNA Repair [NCIt concept]
- Glycosylation [NCIt concept]
- Poly-ADP-Ribosylation [NCIt concept]

Keyword's position in hierarchy(ies) :

You can consult :

recommendations
documents concerning education
documents for patients