Poly [ADP-Ribose] Polymerase 2

Preferred Label : Poly [ADP-Ribose] Polymerase 2;

NCIt synonyms : ADPRT-2; Poly (ADP-Ribose) Polymerase 2; NAD( ) ADP-Ribosyltransferase 2; EC 2.4.2.30; hPARP-2; Poly[ADP-Ribose] Synthase 2; ARTD2; pADPRT-2; ADP-Ribosyltransferase Diphtheria Toxin-Like 2; Poly (ADP-Ribosyl) Transferase-Like 2; Poly(ADP-Ribose) Synthase 2; ADP-Ribosyltransferase 2; ADP-Ribosyltransferase-Like 2; PARP2; PARP-2;

NCIt definition : Poly [ADP-ribose] polymerase 2 (583 aa, 66 kDa) is encoded by the human PARP2 gene. This protein is involved in the initiation of DNA repair.;

Details

Origin ID

C104720;

UMLS CUI

C1436356;

Currated CISMeF NLP mapping
- PARP2 protein, human [MeSH Supplementary Concept]
OMIM relation
- Poly(adp-ribose) polymerase 2 [OMIM gene]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Enzyme [UMLS semantic type]
UMLS correspondences (same concept)
- PARP2 protein, human [MeSH concept]
- PARP2 protein, human [MeSH Supplementary Concept]
concept_is_in_subset
- CTRP Biomarker Terminology [NCIt concept]
- CTRP Molecular Genetic Biomarker Terminology [NCIt concept]
- CTRP Terminology [NCIt concept]
gene_encodes_gene_product
- DNA Repair Gene [NCIt concept]
- Enzyme Gene [NCIt concept]
- Glycosyltransferase Gene [NCIt concept]
- PARP2 Gene [NCIt concept]
- Transferase Gene [NCIt concept]
gene_product_has_associated_anatomy
- Nucleus [NCIt concept]
gene_product_has_structural_domain_or_motif
- Substrate Interaction Domain [NCIt concept]
gene_product_is_element_in_pathway
- Base Excision Repair Pathway [NCIt concept]
- Telomerase Regulation Pathway [NCIt concept]
gene_product_plays_role_in_biological_process
- Base Excision Repair [NCIt concept]
- Carbohydrate Metabolic Process [NCIt concept]
- DNA Repair [NCIt concept]
- Glycosylation [NCIt concept]
- Poly-ADP-Ribosylation [NCIt concept]
- Protein Glycosylation [NCIt concept]
is_target
- Abiraterone Acetate/Niraparib [NCIt concept]
- Carbon C 14 Fluzoparib [NCIt concept]
- Fuzuloparib [NCIt concept]
- Nesuparib [NCIt concept]
- Niraparib [NCIt concept]
- Niraparib Tosylate Monohydrate [NCIt concept]
- Olaparib [NCIt concept]
- PARP 1/2 Inhibitor NOV1401 [NCIt concept]
- PARP 1/2 Inhibitor RP12146 [NCIt concept]
- PARP 1/2 Inhibitor SC10914 [NCIt concept]
- PARP 1/2 Inhibitor TQB3823 [NCIt concept]
- PARP Inhibitor CEP-9722 [NCIt concept]
- PARP Inhibitor E7016 [NCIt concept]
- PARP-1/2 Inhibitor ABT-767 [NCIt concept]
- PARP/Microtubule Polymerization Inhibitor AMXI-5001 [NCIt concept]
- PARP/Tankyrase Inhibitor 2X-121 [NCIt concept]
- Pamiparib [NCIt concept]
- Prodrug PARP Inhibitor TSL-1502 [NCIt concept]
- Rucaparib [NCIt concept]
- Rucaparib Camsylate [NCIt concept]
- Rucaparib Phosphate [NCIt concept]
- Senaparib [NCIt concept]
- Simmiparib [NCIt concept]
- Talazoparib [NCIt concept]
- Talazoparib Tosylate [NCIt concept]
- Veliparib [NCIt concept]
- Venadaparib [NCIt concept]

Keyword's position in hierarchy(ies) :

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