Cytosolic Purine 5'-Nucleotidase

Preferred Label : Cytosolic Purine 5'-Nucleotidase;

NCIt synonyms : Cytosolic 5'-Nucleotidase II; EC 3.1.3.5; IMP-Specific 5'-NT; 5'-Nucleotidase (Purine), Cytosolic Type B; Purine 5' Nucleotidase; NT5C2;

NCIt related terms : Cytosolic Purine 5-Nucleotidase;

NCIt definition : Cytosolic purine 5'-nucleotidase (561 aa, 65 kDa) is encoded by the human NT5C2 gene. This protein plays a role in the maintenance of intracellular purine pools.;

Details

Origin ID

C104589;

UMLS CUI

C1701467;

Automatic exact mappings (from CISMeF team)
- 5'-nucleotidase, cytosolic II [ORDO Gene]
- 5'-nucleotidase, cytosolic II [HGNC gene]
- 5-prime-nucleotidase, cytosolic II [OMIM gene]
- purine 5'-nucleotidase [MeSH concept]
- purine 5'-nucleotidase [MeSH Supplementary Concept]
OMIM relation
- 5-prime-nucleotidase, cytosolic II [OMIM gene]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Enzyme [UMLS semantic type]
UMLS correspondences (same concept)
- NT5C2 protein, human [MeSH concept]
- NT5C2 protein, human [MeSH Supplementary Concept]
concept_is_in_subset
- CTRP Biomarker Terminology [NCIt concept]
- CTRP Molecular Genetic Biomarker Terminology [NCIt concept]
- CTRP Terminology [NCIt concept]
gene_encodes_gene_product
- Enzyme Gene [NCIt concept]
- Esterase Gene [NCIt concept]
- Hydrolase Gene [NCIt concept]
- NT5C2 Gene [NCIt concept]
gene_product_has_associated_anatomy
- Cytosol [NCIt concept]
gene_product_has_biochemical_function
- Hydrolase [NCIt concept]
gene_product_has_chemical_classification
- 5' Nucleotidase Family [NCIt concept]
gene_product_has_gene_product_variant
- NT5C2 NP_001127845.1:p.R367Q [NCIt concept]
- NT5C2 Protein Variant [NCIt concept]
gene_product_has_structural_domain_or_motif
- Substrate Interaction Domain [NCIt concept]
gene_product_is_element_in_pathway
- Nicotinate and Nicotinamide Metabolism Pathway [NCIt concept]
- Purine Metabolism Pathway [NCIt concept]
- Pyrimidine Metabolism Pathway [NCIt concept]
gene_product_plays_role_in_biological_process
- Drug Metabolism Induction [NCIt concept]
- Hydrolysis [NCIt concept]
- Nucleotide Metabolic Process [NCIt concept]
- Phosphorylation Process [NCIt concept]

Keyword's position in hierarchy(ies) :

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