5' Nucleotidase Family

Preferred Label : 5' Nucleotidase Family;

NCIt synonyms : 5'-N'Tase; 5-Nucleotidase; 5'-NT; 5' Nucleotidase; Five Prime Nucleotidase; 5'-NTase;

NCIt definition : A class of enzymes present in various organs and in many cells that catalyze the hydrolysis of a 5'-ribonucleotide to a ribonucleoside and orthophosphate in the presence of water. Serum 5'-N'Tase is measured as an indicator of liver damage resulting primarily from interference with the secretion of bile. Serum 5'-N'Tase is not as sensitive as some other enzymes (for example, ALP, AST, and ALT) to liver damage, but it is a more liver-specific enzyme. The level of this enzyme parallels alkaline phosphatase (ALP). It is used mostly to differentiate elevations in the above enzymes due to liver damage from damage to skeletal muscle.;

NCI Metathesaurus CUI : CL473334;

Details

Origin ID

C19637;

UMLS CUI

C0000530;

Automatic exact mappings (from CISMeF team)
- 2'-nucleotidase [MeSH concept]
- 2'-nucleotidase [MeSH Supplementary Concept]
- 3'-nucleotidase [MeSH concept]
- 3'-nucleotidase [MeSH Supplementary Concept]
- 3'-nucleotidase [SNOMED Notion]
- 3'-nucleotidase (substance) [SNOMED CT concept]
- Nucleotidase (substance) [SNOMED CT concept]
- Pyrimidine-5'-Nucleotidase [LOINC component]
- nucleotidase [MeSH concept]
- nucleotidase [MeSH Supplementary Concept]
- nucleotidase [SNOMED Notion]
False automatic mappings
- 5'-nucleotidase (substance) [SNOMED CT concept]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Enzyme [UMLS semantic type]
- Immunologic Factor [UMLS semantic type]
UMLS correspondences (same concept)
- 5'-Nucleotidase [LOINC component]
- 5'-Nucleotidase [MeSH concept]
- 5'-Nucleotidase [MeSH Descriptor]
- 5'-nucleotidase [SNOMED Notion]
- 5'-nucleotidase (substance) [SNOMED CT concept]
- CD73 [LOINC component]
- Lymphocyte antigen CD73 (substance) [SNOMED CT concept]
- Pyrimidine-5'-Nucleotidase [LOINC component]
- Pyrimidine-5'-nucleotidase (substance) [SNOMED CT concept]
- lymphocyte antigen cd73 [SNOMED Notion]
- pyrimidine-5'-nucleotidase [SNOMED Notion]
gene_product_has_biochemical_function
- Esterase [NCIt concept]
is_chemical_classification_of_gene_product
- 5'-Nucleotidase [NCIt concept]
- Cytosolic 5'-Nucleotidase 1A [NCIt concept]
- Cytosolic 5'-Nucleotidase 3A [NCIt concept]
- Cytosolic Purine 5'-Nucleotidase [NCIt concept]
- Prostatic Acid Phosphatase [NCIt concept]

Keyword's position in hierarchy(ies) :

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