SUMO-Conjugating Enzyme UBC9

Preferred Label : SUMO-Conjugating Enzyme UBC9;

NCIt synonyms : Ubiquitin-Protein Ligase I; RING-Type E3 SUMO Transferase UBC9; UBE2I; Ubiquitin Carrier Protein I; Ubiquitin Conjugating Enzyme E2I; EC 2.3.2.-; Ubiquitin-Protein Ligase E2I; Ubiquitin-Conjugating Enzyme E2I; Ubiquitin-Conjugating Enzyme E2 I; SUMO-Protein Ligase; Ubiquitin Conjugating Enzyme 9; Ubiquitin-Conjugating Enzyme UbcE2A; p18; Ubiquitin-Like Protein SUMO-1 Conjugating Enzyme; Ubiquitin Carrier Protein 9; UBCE9; SUMO-1-Protein Ligase;

NCIt definition : SUMO-conjugating enzyme UBC9 (158 aa, 18 kDa) is encoded by the human UBE2I gene. This protein plays a role in the sumoylation of target proteins.;

Details

Origin ID

C178595;

UMLS CUI

C0534043;

Automatic exact mappings (from CISMeF team)
- Maf bzip transcription factor k [OMIM gene]
- Tubulin polymerization-promoting protein family, member 2 [OMIM gene]
- Ubiquitin-conjugating enzyme e2 I [OMIM gene]
- cyclin dependent kinase inhibitor 2C [ORDO Gene]
- ubiquitin-conjugating enzyme UBC9 [MeSH Supplementary Concept]
OMIM relation
- Ubiquitin-conjugating enzyme e2 I [OMIM gene]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Enzyme [UMLS semantic type]
UMLS correspondences (same concept)
- UBE2I protein, human [MeSH concept]
gene_encodes_gene_product
- Enzyme Gene [NCIt concept]
- Transferase Gene [NCIt concept]
- UBE2I Gene [NCIt concept]
gene_product_has_associated_anatomy
- Cytoplasm [NCIt concept]
- Nucleus [NCIt concept]
gene_product_has_structural_domain_or_motif
- Substrate Interaction Domain [NCIt concept]
- UBC Domain [NCIt concept]
gene_product_is_element_in_pathway
- Coregulation Pathway for Androgen Receptor Activity [NCIt concept]
- HDAC Class I Signaling Pathway [NCIt concept]
- HDAC Class II Signaling Pathway [NCIt concept]
- RANBP2-Mediated Sumoylation Transcription Regulation Pathway [NCIt concept]
- Ubiquitin-mediated Proteolysis Pathway [NCIt concept]
gene_product_plays_role_in_biological_process
- Chromosome Segregation [NCIt concept]
- Post-Translational Modification [NCIt concept]

Keyword's position in hierarchy(ies) :

You can consult :

recommendations
documents concerning education
documents for patients