GTP-Binding Protein Rheb

Preferred Label : GTP-Binding Protein Rheb;

NCIt synonyms : Ras Homolog Enriched In Brain; Ras Homolog Enriched In Brain 2;

NCIt definition : GTP-binding protein Rheb (184 aa, 20 kDa) is encoded by the human RHEB gene. This protein plays a role in the positive regulation of MTORC1-mediated signal transduction.;

NCI Metathesaurus CUI : CL473393;

Details

Origin ID

C115291;

UMLS CUI

C1455621;

Automatic exact mappings (from CISMeF team)
- Ras homolog enriched in brain [OMIM gene]
OMIM relation
- Ras homolog enriched in brain [OMIM gene]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Enzyme [UMLS semantic type]
UMLS correspondences (same concept)
- RHEB protein, human [MeSH Supplementary Concept]
- RHEB protein, human [MeSH concept]
concept_is_in_subset
- CTRP Biomarker Terminology [NCIt concept]
- CTRP Molecular Genetic Biomarker Terminology [NCIt concept]
- CTRP Terminology [NCIt concept]
gene_encodes_gene_product
- Enzyme Gene [NCIt concept]
- Hydrolase Gene [NCIt concept]
- RHEB Gene [NCIt concept]
- Signaling Pathway Gene [NCIt concept]
gene_product_has_associated_anatomy
- Cytosol [NCIt concept]
- Exosome [NCIt concept]
gene_product_has_biochemical_function
- GTPase [NCIt concept]
gene_product_has_structural_domain_or_motif
- GTP Binding Domain [NCIt concept]
- Substrate Interaction Domain [NCIt concept]
gene_product_is_element_in_pathway
- Insulin/Insulin Receptor Signaling Pathway [NCIt concept]
- mTOR Signaling Pathway BioCarta [NCIt concept]
- mTOR Signaling Pathway KEGG [NCIt concept]
- mTOR Signaling Pathway PID [NCIt concept]
gene_product_plays_role_in_biological_process
- GTP Binding [NCIt concept]
- Hydrolysis [NCIt concept]
- Receptor Signaling [NCIt concept]
- Signal Transduction [NCIt concept]
- Signal Transduction Induction [NCIt concept]

Keyword's position in hierarchy(ies) :

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