Arginase-1 - CISMeF

Preferred Label : Arginase-1;

NCIt synonyms : Liver-Type Arginase; EC 3.5.3.1; Type I Arginase; Arginase A1; ARG1; L-Arginine Amidinohydrolase; L-Arginine Ureahydrolase;

NCIt definition : Arginase-1 (322 aa, 35 kDa) is encoded by the human ARG1 gene. This protein plays a role in the cleavage of L-arginine to L-ornithine and urea.;

Details

Origin ID

C103929;

UMLS CUI

C3500855;

Automatic exact mappings (from CISMeF team)
- Arginase 1 [OMIM gene]
- Arginase-1 [LOINC component]
- arginase [MeSH Descriptor]
- arginase 1 [HGNC gene]
- arginase 1 [ORDO Gene]
- arginase A1 [MeSH concept]
OMIM relation
- Arginase 1 [OMIM gene]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Enzyme [UMLS semantic type]
UMLS correspondences (same concept)
- ARG1 protein, human [MeSH concept]
- ARG1 protein, human [MeSH Supplementary Concept]
- Arginase-1 [LOINC component]
concept_is_in_subset
- CTRP Biomarker Terminology [NCIt concept]
- CTRP Molecular Genetic Biomarker Terminology [NCIt concept]
- CTRP Terminology [NCIt concept]
gene_encodes_gene_product
- ARG1 Gene [NCIt concept]
- Enzyme Gene [NCIt concept]
- Hydrolase Gene [NCIt concept]
gene_product_has_associated_anatomy
- Cytoplasm [NCIt concept]
gene_product_has_structural_domain_or_motif
- Substrate Interaction Domain [NCIt concept]
gene_product_is_element_in_pathway
- ATF-2 Transcription Factor Signaling Pathway [NCIt concept]
- Amoebiasis Pathway [NCIt concept]
- Arginine and Proline Metabolism Pathway [NCIt concept]
- IL4-Mediated Signaling Pathway [NCIt concept]
gene_product_plays_role_in_biological_process
- Biogenic Amine Metabolic Process [NCIt concept]
- Catabolic Process [NCIt concept]
- Hydrolysis [NCIt concept]
is_target
- ARG1/ARG2 Inhibitor OATD-02 [NCIt concept]

Keyword's position in hierarchy(ies) :

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