Thymidine Phosphorylase

Preferred Label : Thymidine Phosphorylase;

NCIt synonyms : TP; PD-ECGF; Endothelial Cell Growth Factor 1 (Platelet-Derived); TdRPase; ECGF1; Gliostatin; Thymidylate Phosphorylase; EC 2.4.2.4; Platelet-Derived Endothelial Cell Growth Factor-1; Platelet-Derived Endothelial Cell Growth Factor 1; TYMP;

NCIt definition : Thymidine phosphorylase (482 aa, 50 kDa) is encoded by the human TYMP gene. This protein plays a role in pyrimidine metabolism, DNA replication and endothelial cell migration and tube formation.;

Details

Origin ID

C26148;

UMLS CUI

C2742904;

Currated CISMeF NLP mapping
- Thymidine phosphorylase [LOINC component]
- thymidine phosphorylase [MeSH Descriptor]
- thymidine phosphorylase [MeSH concept]
- thymidine phosphorylase [SNOMED Notion]
False automatic mappings
- Thymidine phosphorylase (substance) [SNOMED CT concept]
OMIM relation
- Thymidine phosphorylase [OMIM gene]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Enzyme [UMLS semantic type]
UMLS correspondences (same concept)
- TYMP protein, human [MeSH Supplementary Concept]
- TYMP protein, human [MeSH concept]
- Thymidine phosphorylase [LOINC component]
- Thymidine phosphorylase (substance) [SNOMED CT concept]
- thymidine phosphorylase [MeSH Descriptor]
- thymidine phosphorylase [MeSH concept]
- thymidine phosphorylase [SNOMED Notion]
concept_is_in_subset
- CTRP Biomarker Terminology [NCIt concept]
- CTRP Molecular Genetic Biomarker Terminology [NCIt concept]
- CTRP Terminology [NCIt concept]
gene_encodes_gene_product
- Enzyme Gene [NCIt concept]
- Glycosyltransferase Gene [NCIt concept]
- TYMP Gene [NCIt concept]
- Transferase Gene [NCIt concept]
gene_product_has_organism_source
- Human [NCIt concept]
gene_product_has_structural_domain_or_motif
- Substrate Interaction Domain [NCIt concept]
gene_product_is_element_in_pathway
- Bladder Cancer Pathway [NCIt concept]
- Drug Metabolism by Non-CYP450 Enzymes Pathway [NCIt concept]
- Pyrimidine Metabolism Pathway [NCIt concept]
gene_product_plays_role_in_biological_process
- Angiogenic Process [NCIt concept]
- Carbohydrate Metabolic Process [NCIt concept]
- Glial Cell Proliferation [NCIt concept]
- Glycosylation [NCIt concept]
- Nucleotide Metabolic Process [NCIt concept]
is_target
- Trifluridine and Tipiracil Hydrochloride [NCIt concept]

Keyword's position in hierarchy(ies) :

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