Arachidonate 5-Lipoxygenase

Preferred Label : Arachidonate 5-Lipoxygenase;

NCIt synonyms : ALOX5; EC 1.13.11.34; 5-LO; 5-Lipoxygenase; 5LOX;

NCIt definition : Arachidonate 5-lipoxygenase protein (674 aa, 78 kDa) is encoded by the human ALOX5 gene. This protein plays a role in the synthesis of leukotrienes from arachidonic acid; thus, it mediates both inflammation and allergen responses.;

Details

Origin ID

C68729;

UMLS CUI

C3711265;

Currated CISMeF NLP mapping
- Arachidonate 5-lipoxygenase (substance) [SNOMED CT concept]
- arachidonate 5-lipoxygenase [SNOMED Notion]
OMIM relation
- Arachidonate 5-lipoxygenase [OMIM gene]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Enzyme [UMLS semantic type]
UMLS correspondences (same concept)
- ALOX5 protein, human [MeSH Supplementary Concept]
- ALOX5 protein, human [MeSH concept]
- Arachidonate 5-lipoxygenase (substance) [SNOMED CT concept]
- arachidonate 5-Lipoxygenase [MeSH concept]
- arachidonate 5-lipoxygenase [MeSH Descriptor]
- arachidonate 5-lipoxygenase [SNOMED Notion]
concept_is_in_subset
- CTRP Biomarker Terminology [NCIt concept]
- CTRP Molecular Genetic Biomarker Terminology [NCIt concept]
- CTRP Terminology [NCIt concept]
gene_encodes_gene_product
- ALOX5 Gene [NCIt concept]
- Enzyme Gene [NCIt concept]
- Oxidoreductase Gene [NCIt concept]
gene_product_has_structural_domain_or_motif
- Substrate Interaction Domain [NCIt concept]
gene_product_is_element_in_pathway
- Prostaglandin and Leukotriene Metabolism Pathway [NCIt concept]
gene_product_plays_role_in_biological_process
- Lipid Metabolic Process [NCIt concept]
- Oxidation [NCIt concept]
- Oxidation/Reduction [NCIt concept]
is_target
- Boswellia serrata Extract [NCIt concept]
- Masoprocol [NCIt concept]

Keyword's position in hierarchy(ies) :

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