Preferred Label : arachidonate 5-lipoxygenase;
MeSH definition : An enzyme that catalyzes the oxidation of arachidonic acid to yield 5-hydroperoxyarachidonate
(5-HPETE) which is rapidly converted by a peroxidase to 5-hydroxy-6,8,11,14-eicosatetraenoate
(5-HETE). The 5-hydroperoxides are preferentially formed in leukocytes.;
MeSH synonym : leukotriene a synthase; lta4 synthase; synthase, leukotriene a4; synthetase, leukotriene a4; 5-lipoxygenase, arachidonate; 5-lipoxygenase, arachidonic acid; 5-lipoxygenase; 5 lipoxygenase; synthase, leukotriene a; arachidonic acid 5-lipoxygenase; arachidonic acid 5 lipoxygenase; synthase, lta4; leukotriene a4 synthase; leukotriene a4 synthetase; arachidonate 5 lipoxygenase;
MeSH CAS label : arachidonate:oxygen 5-oxidoreductase;
Registry Number MeSH : EC 1.13.11.34;
Wikipedia link : https://en.wikipedia.org/wiki/Arachidonate 5-lipoxygenase;
Is substance : O;
UNII : EC 1.13.11.34;
Origin ID : D001094;
UMLS CUI : C0003693;
Allowable qualifiers
Indexing information
- 5-Loxin [MeSH Supplementary Concept]
- CMI 392 [MeSH Supplementary Concept]
- S 29606 [MeSH Supplementary Concept]
- S 30621 [MeSH Supplementary Concept]
Record concept(s)
Related MeSH Supplementary Concept(s)
Related MeSH term(s)
Semantic type(s)
UMLS correspondences (same concept)
An enzyme that catalyzes the oxidation of arachidonic acid to yield 5-hydroperoxyarachidonate
(5-HPETE) which is rapidly converted by a peroxidase to 5-hydroxy-6,8,11,14-eicosatetraenoate
(5-HETE). The 5-hydroperoxides are preferentially formed in leukocytes.