Transcriptional Intermediary Factor 1-Beta

Preferred Label : Transcriptional Intermediary Factor 1-Beta;

NCIt synonyms : RING-Type E3 Ubiquitin Transferase TIF1-Beta; KRIP-1; Tripartite Motif-Containing Protein 28; Tripartite Motif-Containing 28; EC 2.3.2.27; KRAB-Interacting Protein 1; TIF1-Beta; KAP-1; KRAB-Associated Protein 1; RING Finger Protein 96; TRIM28; E3 SUMO-Protein Ligase TRIM28; Nuclear Corepressor KAP-1;

NCIt definition : Transcription intermediary factor 1-beta (835 aa, 89 kDa) is encoded by the human TRIM28 gene. This protein is involved in the inhibition of herpesvirus 8-mediated cell lysis, transcriptional repression, chromatin remodeling and protein sumoylation.;

Details

Origin ID

C177185;

UMLS CUI

C1456422;

Automatic exact mappings (from CISMeF team)
- Tripartite Motif-Containing Protein 28 [MeSH Descriptor]
- Tripartite Motif-Containing Protein 28 [MeSH concept]
- Tripartite motif-containing protein 28 [OMIM gene]
- tripartite motif containing 28 [HGNC gene]
- tripartite motif containing 28 [ORDO Gene]
OMIM relation
- Tripartite motif-containing protein 28 [OMIM gene]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Biologically Active Substance [UMLS semantic type]
UMLS correspondences (same concept)
- TRIM28 protein, human [MeSH Supplementary Concept]
- TRIM28 protein, human [MeSH concept]
concept_is_in_subset
- CTRP Biomarker Terminology [NCIt concept]
- CTRP Molecular Genetic Biomarker Terminology [NCIt concept]
- CTRP Terminology [NCIt concept]
gene_encodes_gene_product
- Enzyme Gene [NCIt concept]
- Regulatory Gene [NCIt concept]
- TRIM28 Gene [NCIt concept]
- Transcription Regulation Gene [NCIt concept]
- Transferase Gene [NCIt concept]
gene_product_has_associated_anatomy
- Nucleus [NCIt concept]
gene_product_has_biochemical_function
- TRIM Family [NCIt concept]
- Transcription Repressor/Corepressor [NCIt concept]
gene_product_has_structural_domain_or_motif
- Bromodomain [NCIt concept]
- Coiled-Coil Domain [NCIt concept]
- PHD Finger [NCIt concept]
- Ring Finger Domain [NCIt concept]
- Substrate Interaction Domain [NCIt concept]
- TRIM Motif [NCIt concept]
gene_product_is_element_in_pathway
- E2F Transcription Factor Pathway [NCIt concept]
- p53 Pathway for Transcriptional Regulation [NCIt concept]
gene_product_plays_role_in_biological_process
- Antiviral Response [NCIt concept]
- Chromatin Remodeling [NCIt concept]
- Post-Translational Modification [NCIt concept]
- Transcriptional Regulation [NCIt concept]

Keyword's position in hierarchy(ies) :

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