Preferred Label : Bromodomain;
NCIt definition : A motif common in chromatin remodeling factors. It consists of approximately 110 amino
acids in a left-handed up-and-down four helix bundle with a left handed twist. A hydrophobic
pocket in the bromodomain creates an acetyl-lysine binding domain. Bromodomain-containing
proteins may recruit remodeling complexes to acetylated chromatin regions.;
Origin ID : C13732;
UMLS CUI : C1511331;
Semantic type(s)
is_structural_domain_or_motif_of_gene_product