" /> Bromodomain Adjacent to Zinc Finger Domain Protein 1A - CISMeF





Preferred Label : Bromodomain Adjacent to Zinc Finger Domain Protein 1A;

NCIt synonyms : ATP-Utilizing Chromatin Assembly and Remodeling Factor 1; hACF1; CHRAC Subunit ACF1; hWALp1; Williams Syndrome Transcription Factor-Related Chromatin-Remodeling Factor 180; ATP-Dependent Chromatin Remodeling Protein; WCRF180; ATP-Dependent Chromatin-Remodeling Protein; BAZ1A;

NCIt definition : Bromodomain adjacent to zinc finger domain protein 1A (1556 aa, 179 kDa) is encoded by the human BAZ1A gene. This protein plays a role in ATP-dependent chromatin remodeling.;

NCIt note : Bromodomain adjacent to zinc finger domain protein 1A is a non-catalytic accessory subunit for the ATP-utilizing chromatin assembly and remodeling factor protein complex (ACF), an ATP-dependent chromatin remodeling complex that regulates nucleosome spacing. SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 5 (SMARCA5) is the catalytic ATPase in the ACF complex. (UniProt); Bromodomain adjacent to zinc finger domain protein 1A is a subunit in the chromatin accessibility complex (CHRAC), which enhances the activity of the ACF complex. CHRAC also contains SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 5 (SMARCA5), DNA polymerase epsilon subunit 3 (POLE3) and CHRAC1. (UniProt);

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17/05/2024


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