PH Domain Leucine-Rich Repeat-Containing Protein Phosphatase 2

Preferred Label : PH Domain Leucine-Rich Repeat-Containing Protein Phosphatase 2;

NCIt synonyms : PHLPP-Like; PH Domain Leucine-Rich Repeat-Containing Protein Phosphatase-Like; PH Domain and Leucine Rich Repeat Protein Phosphatase-Like; EC 3.1.3.16; PH Domain and Leucine-Rich Repeat Protein Phosphatase-Like; PHLPP2;

NCIt definition : PH domain leucine-rich repeat-containing protein phosphatase 2 (1323 aa, 147 kDa) is encoded by the human PHLPP2 gene. This protein is involved in the regulation of apoptosis and may act as a tumor suppressor.;

Details

Origin ID

C107127;

UMLS CUI

C2716679;

Automatic exact mappings (from CISMeF team)
- Ph domain and leucine-rich repeat protein phosphatase-like [OMIM gene]
OMIM relation
- Ph domain and leucine-rich repeat protein phosphatase-like [OMIM gene]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Enzyme [UMLS semantic type]
UMLS correspondences (same concept)
- PHLPP2 protein, human [MeSH Supplementary Concept]
- PHLPP2 protein, human [MeSH concept]
concept_is_in_subset
- CTRP Biomarker Terminology [NCIt concept]
- CTRP Molecular Genetic Biomarker Terminology [NCIt concept]
- CTRP Terminology [NCIt concept]
gene_encodes_gene_product
- Enzyme Gene [NCIt concept]
- Esterase Gene [NCIt concept]
- Hydrolase Gene [NCIt concept]
- PHLPP2 Gene [NCIt concept]
- Phosphatase Family Gene [NCIt concept]
- Protein Phosphatase Gene [NCIt concept]
- Protein Serine/Threonine Phosphatase Gene [NCIt concept]
gene_product_has_biochemical_function
- Hydrolase [NCIt concept]
gene_product_has_structural_domain_or_motif
- Substrate Interaction Domain [NCIt concept]
gene_product_plays_role_in_biological_process
- Dephosphorylation [NCIt concept]
- Hydrolysis [NCIt concept]
- Protein Dephosphorylation [NCIt concept]
- Signal Transduction [NCIt concept]

Keyword's position in hierarchy(ies) :

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