Histone Acetyltransferase p300

Preferred Label : Histone Acetyltransferase p300;

NCIt synonyms : p300 E1A-Associated Coactivator; EP300; E1A-Binding Protein, 300kD; E1A-Associated p300 Protein; EC 2.3.1.48; p300; E1A-Associated Protein p300; E1A Binding Protein p300; p300 HAT; E1A-Binding Protein, 300-kD; E1A Binding Protein-p300; Protein Propionyltransferase P300; Histone Crotonyltransferase P300; Histone Butyryltransferase P300;

NCIt definition : Histone acetyltransferase p300 (2414 aa, 264 kDa) is encoded by the human EP300 gene. This protein is involved in histone acetylation, transcriptional regulation and development.;

UNII : 7U1VP195ST;

Details

Origin ID

C17804;

UMLS CUI

C1530358;

Automatic exact mappings (from CISMeF team)
- ADA3 protein, Drosophila [MeSH Supplementary Concept]
- Ada2a protein, Drosophila [MeSH Supplementary Concept]
- At1g77540 protein, arabidopsis [MeSH Supplementary Concept]
- CBP-1 protein, C elegans [MeSH Supplementary Concept]
- CLOCK protein, human [MeSH Supplementary Concept]
- CLOCK proteins [MeSH Descriptor]
- E1A binding protein p300 [HGNC gene]
- E1A binding protein p300 [ORDO Gene]
- E1a-binding protein, 300-kd [OMIM gene]
- ELO3 protein, arabidopsis [MeSH Supplementary Concept]
- ELP3 protein, drosophila [MeSH Supplementary Concept]
- ELP3 protein, human [MeSH Supplementary Concept]
- ELP3 protein, zebrafish [MeSH Supplementary Concept]
- EP300 protein, human [MeSH Supplementary Concept]
- Eaf1 protein, S cerevisiae [MeSH Supplementary Concept]
- Elp3 protein, S cerevisiae [MeSH Supplementary Concept]
- Esa1 protein, S cerevisiae [MeSH Supplementary Concept]
- GCN5 protein, Drosophila [MeSH Supplementary Concept]
- GCN5 protein, S cerevisiae [MeSH Supplementary Concept]
- GCN5 protein, arabidopsis [MeSH Supplementary Concept]
- Gcn5 protein, S pombe [MeSH Supplementary Concept]
- Gcn5l2 protein, mouse [MeSH Supplementary Concept]
- HTATIP2 protein, human [MeSH Supplementary Concept]
- IDM1 protein, arabidopsis [MeSH Supplementary Concept]
- IKI3 protein, S cerevisiae [MeSH Supplementary Concept]
- KAT2A protein, human [MeSH Supplementary Concept]
- KAT6A protein, human [MeSH Supplementary Concept]
- KAT6B protein, human [MeSH Supplementary Concept]
- KAT7 protein, Xenopus [MeSH Supplementary Concept]
- KAT7 protein, human [MeSH Supplementary Concept]
- KAT8 protein, human [MeSH Supplementary Concept]
- Kat2a protein, rat [MeSH Supplementary Concept]
- Kat6a protein, rat [MeSH Supplementary Concept]
- Kat6b protein, mouse [MeSH Supplementary Concept]
- Kat7 protein, mouse [MeSH Supplementary Concept]
- Kat7 protein, rat [MeSH Supplementary Concept]
- MOZ protein, mouse [MeSH Supplementary Concept]
- MSL1 protein, human [MeSH Supplementary Concept]
- MSL1 protein, mouse [MeSH Supplementary Concept]
- MYS-1 protein, C elegans [MeSH Supplementary Concept]
- NAT4 protein, S cerevisiae [MeSH Supplementary Concept]
- NCOA1 protein, human [MeSH Supplementary Concept]
- NCOA3 protein, human [MeSH Supplementary Concept]
- Ncoa3 protein, mouse [MeSH Supplementary Concept]
- NuA4 protein, S cerevisiae [MeSH Supplementary Concept]
- OGA protein, human [MeSH Supplementary Concept]
- P-300 [MeSH concept]
- P-300 [MeSH Supplementary Concept]
- Rtt109 protein, S cerevisiae [MeSH Supplementary Concept]
- Rtt109 protein, S pombe [MeSH Supplementary Concept]
- SAS3 protein, S cerevisiae [MeSH Supplementary Concept]
- SGF29 protein, rat [MeSH Supplementary Concept]
- SPT10 protein, S cerevisiae [MeSH Supplementary Concept]
- Sas2 protein, S cerevisiae [MeSH Supplementary Concept]
- Sgf29 protein, S cerevisiae [MeSH Supplementary Concept]
- Sgf73 protein, S cerevisiae [MeSH Supplementary Concept]
- Tip60 protein, drosophila [MeSH Supplementary Concept]
- Yng1 protein, S cerevisiae [MeSH Supplementary Concept]
- clock protein, mouse [MeSH Supplementary Concept]
- clock protein, rat [MeSH Supplementary Concept]
- creb-binding protein [MeSH Descriptor]
- histone acetyltransferase type B complex [MeSH Supplementary Concept]
- histone acetyltransferases [MeSH Descriptor]
- kat6a protein, zebrafish [MeSH Supplementary Concept]
- nuclear receptor coactivator 1 [MeSH Descriptor]
- nuclear receptor coactivator 3 [MeSH Descriptor]
- p300-CBP-associated factor [MeSH Supplementary Concept]
- p300-cbp transcription factors [MeSH Descriptor]
- sucrase [MeSH Descriptor]
- tGCN5 histone acetyltransferase [MeSH Supplementary Concept]
Currated CISMeF NLP mapping
- E1A-Associated p300 protein [MeSH concept]
- e1a-associated p300 protein [MeSH Descriptor]
OMIM relation
- E1a-binding protein, 300-kd [OMIM gene]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Biologically Active Substance [UMLS semantic type]
UMLS correspondences (same concept)
- EP300 protein, human [MeSH concept]
- EP300 protein, human [MeSH Supplementary Concept]
concept_is_in_subset
- CTRP Biomarker Terminology [NCIt concept]
- CTRP Molecular Genetic Biomarker Terminology [NCIt concept]
- CTRP Terminology [NCIt concept]
- FDA Established Names and Unique Ingredient Identifier Codes Terminology [NCIt concept]
gene_encodes_gene_product
- EP300 Gene [NCIt concept]
- Enzyme Gene [NCIt concept]
- Transferase Gene [NCIt concept]
gene_product_has_biochemical_function
- Chromatin Remodeling Factor [NCIt concept]
- Transcription Coactivator [NCIt concept]
gene_product_has_structural_domain_or_motif
- Substrate Interaction Domain [NCIt concept]
gene_product_is_element_in_pathway
- ATF-2 Transcription Factor Signaling Pathway [NCIt concept]
- Adherens Junction Assembly Pathway [NCIt concept]
- CARM1 Transcription Regulation Pathway [NCIt concept]
- Cell Cycle Pathway [NCIt concept]
- ERBB2 Signaling Pathway [NCIt concept]
- Estrogen Receptor Regulation by CARM1 Pathway [NCIt concept]
- G2/M Checkpoint Pathway [NCIt concept]
- Gene Expression Regulation by Vitamin D Receptor Pathway [NCIt concept]
- HDAC Class III Signaling Pathway [NCIt concept]
- Huntington's Disease Pathway [NCIt concept]
- Hypoxia Pathway [NCIt concept]
- Hypoxia-Inducible Factor Pathway [NCIt concept]
- IL7 Signaling Pathway [NCIt concept]
- Jak-STAT Signaling Pathway [NCIt concept]
- Long-Term Potentiation Pathway [NCIt concept]
- Melanocyte Development Pathway [NCIt concept]
- Melanogenesis Pathway [NCIt concept]
- NFKB Activation Pathway [NCIt concept]
- Notch Signaling Pathway [NCIt concept]
- Obesity and Thermogenesis Pathway [NCIt concept]
- PPAR-alpha Gene Regulation Pathway [NCIt concept]
- Pelp1 Estrogen Receptor Pathway [NCIt concept]
- Pitx2 Transcription Regulation Pathway [NCIt concept]
- Prostate Cancer Pathway [NCIt concept]
- RELA Pathway [NCIt concept]
- Regulation of Nuclear SMAD2/3 Signaling Pathway [NCIt concept]
- Renal Cell Carcinoma Pathway [NCIt concept]
- T-Cell Apoptosis Pathway [NCIt concept]
- TGF Beta Signaling Pathway BioCarta [NCIt concept]
- TGF-beta Signaling Pathway KEGG [NCIt concept]
- Wnt Signaling Pathway KEGG [NCIt concept]
gene_product_plays_role_in_biological_process
- Chromatin Remodeling [NCIt concept]
- Histone Acetylation [NCIt concept]
- Transcriptional Regulation [NCIt concept]
is_target
- BET/CBP/p300 Inhibitor EP31670 [NCIt concept]
- CBP/p300 Bromodomain Inhibitor FT-7051 [NCIt concept]

Keyword's position in hierarchy(ies) :

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