MeSH definition : A nuclear receptor coactivator with specificity for ESTROGEN RECEPTORS and PROGESTERONE
RECEPTORS. It contains a histone acetyltransferase activity that may play a role in
CHROMATIN REMODELING during the process of nuclear receptor-induced transcription.
The coactivator has been found at elevated levels in certain HORMONE-DEPENDENT NEOPLASMS
such as those found in BREAST CANCER.;
MeSH synonym : amplified in breast cancer 1 protein; steroid receptor coactivator 3; thyroid hormone receptor activator molecule 1; Receptor-Associated coactivator 3; receptor associated coactivator 3; amplified in breast Cancer-1 protein; nuclear receptor Coactivator-3;
A nuclear receptor coactivator with specificity for ESTROGEN RECEPTORS and PROGESTERONE
RECEPTORS. It contains a histone acetyltransferase activity that may play a role in
CHROMATIN REMODELING during the process of nuclear receptor-induced transcription.
The coactivator has been found at elevated levels in certain HORMONE-DEPENDENT NEOPLASMS
such as those found in BREAST CANCER.