MeSH definition : A family of histone acetyltransferases that is structurally-related to CREB-BINDING
PROTEIN and to E1A-ASSOCIATED P300 PROTEIN. They function as transcriptional coactivators
by bridging between DNA-binding TRANSCRIPTION FACTORS and the basal transcription
machinery. They also modify transcription factors and CHROMATIN through ACETYLATION.;
A family of histone acetyltransferases that is structurally-related to CREB-BINDING
PROTEIN and to E1A-ASSOCIATED P300 PROTEIN. They function as transcriptional coactivators
by bridging between DNA-binding TRANSCRIPTION FACTORS and the basal transcription
machinery. They also modify transcription factors and CHROMATIN through ACETYLATION.