Arachidonate 12-Lipoxygenase, 12S-Type

Preferred Label : Arachidonate 12-Lipoxygenase, 12S-Type;

NCIt synonyms : 12S-Lipoxygenase; Platelet-Type Lipoxygenase 12; EC 1.13.11.31; ALOX12; 12S-LOX;

NCIt definition : Arachidonate 12-lipoxygenase, 12S-type (663 aa, 76 kDa) is encoded by the human ALOX12 gene. This protein plays a role in both fatty acid oxidation and leukotriene biosynthesis.;

Details

Origin ID

C103926;

UMLS CUI

C3538937;

OMIM relation
- Arachidonate 12-oxidoreductase [OMIM gene]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Enzyme [UMLS semantic type]
concept_is_in_subset
- CTRP Biomarker Terminology [NCIt concept]
- CTRP Molecular Genetic Biomarker Terminology [NCIt concept]
- CTRP Terminology [NCIt concept]
gene_encodes_gene_product
- ALOX12 Gene [NCIt concept]
- Enzyme Gene [NCIt concept]
- Oxidoreductase Gene [NCIt concept]
gene_product_has_associated_anatomy
- Cytoplasm [NCIt concept]
- Sarcolemma [NCIt concept]
gene_product_has_structural_domain_or_motif
- Substrate Interaction Domain [NCIt concept]
gene_product_is_element_in_pathway
- Arachidonic Acid Metabolism Pathway [NCIt concept]
gene_product_plays_role_in_biological_process
- Fatty Acid Metabolism [NCIt concept]
- Leukotriene Production [NCIt concept]
- Oxidation [NCIt concept]
- Oxidation/Reduction [NCIt concept]
is_target
- 12-Lipoxygenase Inhibitor VLX-1005 [NCIt concept]

Keyword's position in hierarchy(ies) :

You can consult :

recommendations
documents concerning education
documents for patients