Sphingomyelin Phosphodiesterase 2

Preferred Label : Sphingomyelin Phosphodiesterase 2;

NCIt synonyms : N-SMase; EC 3.1.4.12; SMPD2; nSMase; Neutral Sphingomyelinase; Lyso-PAF-PLC; Lyso-Platelet-Activating Factor-Phospholipase C;

NCIt definition : Sphingomyelin phosphodiesterase 2 (423 aa, 48 kDa) is encoded by the human SMPD2 gene. This protein is involved in phospholipid metabolism.;

Details

Origin ID

C105026;

UMLS CUI

C3539580;

OMIM relation
- Sphingomyelin phosphodiesterase 2, neutral membrane [OMIM gene]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Enzyme [UMLS semantic type]
concept_is_in_subset
- CTRP Biomarker Terminology [NCIt concept]
- CTRP Molecular Genetic Biomarker Terminology [NCIt concept]
- CTRP Terminology [NCIt concept]
gene_encodes_gene_product
- Enzyme Gene [NCIt concept]
- Esterase Gene [NCIt concept]
- Hydrolase Gene [NCIt concept]
- SMPD2 Gene [NCIt concept]
gene_product_has_associated_anatomy
- Plasma Membrane [NCIt concept]
gene_product_has_biochemical_function
- Hydrolase [NCIt concept]
gene_product_has_structural_domain_or_motif
- Substrate Interaction Domain [NCIt concept]
gene_product_is_element_in_pathway
- Ceramide Signaling Pathway BioCarta [NCIt concept]
- Nerve Growth Factor Receptor Signaling Pathway [NCIt concept]
- Sphingolipid Metabolism Pathway [NCIt concept]
- TNF Receptor Family Signaling Pathway [NCIt concept]
gene_product_plays_role_in_biological_process
- Hydrolysis [NCIt concept]
- Phospholipid Metabolism [NCIt concept]
- Signal Transduction [NCIt concept]

Keyword's position in hierarchy(ies) :

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