Aspartate Aminotransferase, Mitochondrial

Preferred Label : Aspartate Aminotransferase, Mitochondrial;

NCIt synonyms : Mitochondrial Aspartate Aminotransferase; Transaminase A; Glutamate Oxaloacetate Transaminase-2; GOT2; Mitochondrial Glutamic-Oxaloacetic Transaminase 2; Fatty Acid-Binding Protein; Glutamate Oxaloacetate Transaminase 2; FABP-1; EC 2.6.1.1; mAspAT; Plasma Membrane-Associated Fatty Acid-Binding Protein; Aspartate Aminotransferase 2; FABPpm; Aspartate Aminotransferase-2;

NCIt definition : Aspartate aminotransferase, mitochondrial (430 aa, 48 kDa) is encoded by the human GOT2 gene. This protein plays a role in both the metabolism of amino acids and fatty acid transport.;

NCIt note : Protein_Plays_Role_In_Biological_Process: Urea Cycle, Tricarboxylic Acid Cycle, Transamination;

Details

Origin ID

C38502;

UMLS CUI

C5441788;

OMIM relation
- Glutamate oxaloacetate transaminase, mitochondrial [OMIM gene]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Enzyme [UMLS semantic type]
UMLS correspondences (same concept)
- GOT2 protein, human [MeSH Supplementary Concept]
- aspartate aminotransferase, mitochondrial [MeSH concept]
- aspartate aminotransferase, mitochondrial [MeSH Descriptor]
Validated automatic mappings to NTBT
- Aspartate aminotransferase [LOINC component]
- Aspartate aminotransferase (substance) [SNOMED CT concept]
gene_encodes_gene_product
- Enzyme Gene [NCIt concept]
- GOT2 Gene [NCIt concept]
- Transferase Gene [NCIt concept]
gene_product_has_structural_domain_or_motif
- Substrate Interaction Domain [NCIt concept]
gene_product_is_element_in_pathway
- Alanine, Aspartate and Glutamate Metabolism Pathway [NCIt concept]
- Arginine and Proline Metabolism Pathway [NCIt concept]
- Cysteine and Methionine Metabolism Pathway [NCIt concept]
- Phenylalanine Metabolism Pathway [NCIt concept]
- Phenylalanine, Tyrosine and Tryptophan Biosynthesis Pathway [NCIt concept]
- Tyrosine Metabolism Pathway [NCIt concept]
gene_product_plays_role_in_biological_process
- Protein Metabolism Process [NCIt concept]

Keyword's position in hierarchy(ies) :

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