Folylpolyglutamate Synthase, Mitochondrial

Preferred Label : Folylpolyglutamate Synthase, Mitochondrial;

NCIt synonyms : Folylpoly-Gamma-Glutamate Synthetase; FPGS; Tetrahydrofolate Synthase; EC 6.3.2.17; Tetrahydrofolylpolyglutamate Synthase;

NCIt definition : Folylpolyglutamate synthase, mitochondrial (587 aa, 65 kDa) is encoded by the human FPGS gene. This protein plays a role in the conversion of folates to polyglutamate derivatives.;

Details

Origin ID

C103942;

UMLS CUI

C3539658;

Automatic exact mappings (from CISMeF team)
- Folylpolyglutamate synthetase [OMIM gene]
- folylpolyglutamate synthetase [MeSH Supplementary Concept]
OMIM relation
- Folylpolyglutamate synthetase [OMIM gene]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Enzyme [UMLS semantic type]
concept_is_in_subset
- CTRP Biomarker Terminology [NCIt concept]
- CTRP Molecular Genetic Biomarker Terminology [NCIt concept]
- CTRP Terminology [NCIt concept]
gene_encodes_gene_product
- Enzyme Gene [NCIt concept]
- FPGS Gene [NCIt concept]
- Ligase Gene [NCIt concept]
gene_product_has_associated_anatomy
- Cytosol [NCIt concept]
- Mitochondrial Matrix [NCIt concept]
gene_product_has_structural_domain_or_motif
- Substrate Interaction Domain [NCIt concept]
gene_product_is_element_in_pathway
- Folate Biosynthesis Pathway [NCIt concept]
gene_product_plays_role_in_biological_process
- Folic Acid Metabolic Process [NCIt concept]

Keyword's position in hierarchy(ies) :

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