Ras-Related C3 Botulinum Toxin Substrate 2

Preferred Label : Ras-Related C3 Botulinum Toxin Substrate 2;

NCIt synonyms : GX; p21-Rac2; RAC2; Rac Family Small GTPase 2;

NCIt definition : Ras-related C3 botulinum toxin substrate 2 (192 aa, 21 kDa) is encoded by the human RAC2 gene. This protein is involved in GTPase-dependent regulation of NADPH-oxidase activity.;

Details

Origin ID

C179401;

UMLS CUI

C1740187;

Automatic exact mappings (from CISMeF team)
- Rac family small GTPase 2 [ORDO Gene]
- Rac family small GTPase 2 [HGNC gene]
- Ras-related c3 botulinum toxin substrate 2 [OMIM gene]
- glycinexylidide [MeSH Supplementary Concept]
OMIM relation
- Ras-related c3 botulinum toxin substrate 2 [OMIM gene]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Enzyme [UMLS semantic type]
UMLS correspondences (same concept)
- RAC2 protein, human [MeSH concept]
concept_is_in_subset
- CTRP Biomarker Terminology [NCIt concept]
- CTRP Molecular Genetic Biomarker Terminology [NCIt concept]
- CTRP Terminology [NCIt concept]
gene_encodes_gene_product
- Enzyme Gene [NCIt concept]
- Hydrolase Gene [NCIt concept]
- RAC2 Gene [NCIt concept]
- Signaling Pathway Gene [NCIt concept]
gene_product_has_associated_anatomy
- Cytosol [NCIt concept]
- Hematopoietic and Lymphoid Cell [NCIt concept]
- Plasma Membrane [NCIt concept]
gene_product_has_biochemical_function
- GTPase [NCIt concept]
gene_product_has_structural_domain_or_motif
- GTP Binding Domain [NCIt concept]
- Substrate Interaction Domain [NCIt concept]
gene_product_is_element_in_pathway
- Actin Cytoskeleton Regulation Pathway [NCIt concept]
- Adherens Junction Assembly Pathway [NCIt concept]
- Axon Guidance Pathway [NCIt concept]
- B Cell Receptor Signaling Pathway [NCIt concept]
- Chemokine Signaling Pathway [NCIt concept]
- Colorectal Cancer Pathway [NCIt concept]
- Fc Epsilon Receptor I Signaling Pathway KEGG [NCIt concept]
- Fc Gamma Receptor-Mediated Phagocytosis Pathway [NCIt concept]
- Focal Adhesion Pathway [NCIt concept]
- Leukocyte Transendothelial Migration Pathway [NCIt concept]
- MAPK Signaling Pathway [NCIt concept]
- Natural Killer Cell-Mediated Cytotoxicity Pathway [NCIt concept]
- Pancreatic Cancer Pathway [NCIt concept]
- Prion Disease Pathway [NCIt concept]
- VEGF Signaling Pathway [NCIt concept]
- Viral Myocarditis Pathway [NCIt concept]
- Wnt Signaling Pathway KEGG [NCIt concept]
gene_product_plays_role_in_biological_process
- Cytoskeletal Modeling [NCIt concept]
- GTP Binding [NCIt concept]
- Hydrolysis [NCIt concept]
- Oxidative Burst [NCIt concept]
- Regulation of Cell Shape [NCIt concept]
- Signal Transduction [NCIt concept]

Keyword's position in hierarchy(ies) :

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