E3 SUMO-Protein Ligase EGR2

Preferred Label : E3 SUMO-Protein Ligase EGR2;

NCIt synonyms : Early Growth Response Protein 2; EGR-2; Krox-20 Homolog; AT591; E3 SUMO-Protein Transferase ERG2; Zinc Finger Protein Krox-20; EC 6.3.2.-, Formerly; EGR2; EC 2.3.2.-;

NCIt definition : E3 SUMO-protein ligase EGR2 (476 aa, 50 kDa) is encoded by the human EGR2 gene. This protein plays a role in both protein sumoylation and sequence-specific DNA binding.;

Details

Origin ID

C131314;

UMLS CUI

C1505738;

Automatic exact mappings (from CISMeF team)
- Early growth response 2 [OMIM gene]
- early growth response 2 [HGNC gene]
- early growth response 2 [ORDO Gene]
- early growth response protein 2 [MeSH concept]
- early growth response protein 2 [MeSH Descriptor]
OMIM relation
- Early growth response 2 [OMIM gene]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Enzyme [UMLS semantic type]
UMLS correspondences (same concept)
- EGR2 protein, human [MeSH Supplementary Concept]
- EGR2 protein, human [MeSH concept]
gene_encodes_gene_product
- EGR2 Gene [NCIt concept]
- Enzyme Gene [NCIt concept]
- Ligase Gene [NCIt concept]
- Regulatory Gene [NCIt concept]
- Transcription Factor Gene [NCIt concept]
- Transcription Regulation Gene [NCIt concept]
- Transferase Gene [NCIt concept]
gene_product_has_associated_anatomy
- Nucleus [NCIt concept]
gene_product_has_biochemical_function
- DNA Binding Protein [NCIt concept]
- Sequence-Specific DNA Binding Protein [NCIt concept]
gene_product_has_structural_domain_or_motif
- C2H2 Zinc Finger [NCIt concept]
- Substrate Interaction Domain [NCIt concept]
gene_product_is_element_in_pathway
- T-Cell Antiapoptosis Pathway [NCIt concept]
gene_product_plays_role_in_biological_process
- DNA Binding [NCIt concept]
- Post-Translational Modification [NCIt concept]
- Transcriptional Regulation [NCIt concept]

Keyword's position in hierarchy(ies) :

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