early growth response protein 2

Preferred Label : early growth response protein 2;

MeSH definition : An early growth response transcription factor that controls the formation of the MYELIN SHEATH around peripheral AXONS by SCHWANN CELLS. Mutations in EGR2 transcription factor have been associated with HEREDITARY MOTOR AND SENSORY NEUROPATHIES such as CHARCOT-MARIE-TOOTH DISEASE.;

MeSH synonym : egr2 transcription factor; krox 20 transcription factor; krox20 protein; krox-20 transcription factor; transcription factor, krox-20; transcription factor, egr2;

Is substance : O;

Details

Origin ID

D051767;

UMLS CUI

C0064419;

Allowable qualifiers
- administration and dosage [MeSH Qualifier]
- adverse effects [MeSH Qualifier]
- agonists [MeSH Qualifier]
- analysis [MeSH Qualifier]
- antagonists and inhibitors [MeSH Qualifier]
- biosynthesis [MeSH Qualifier]
- blood [MeSH Qualifier]
- cerebrospinal fluid [MeSH Qualifier]
- chemical synthesis [MeSH Qualifier]
- chemistry [MeSH Qualifier]
- classification [MeSH Qualifier]
- contraindications [MeSH Qualifier]
- deficiency [MeSH Qualifier]
- drug effects [MeSH Qualifier]
- economics [MeSH Qualifier]
- genetics [MeSH Qualifier]
- history [MeSH Qualifier]
- immunology [MeSH Qualifier]
- isolation and purification [MeSH Qualifier]
- metabolism [MeSH Qualifier]
- pharmacokinetics [MeSH Qualifier]
- pharmacology [MeSH Qualifier]
- physiology [MeSH Qualifier]
- poisoning [MeSH Qualifier]
- radiation effects [MeSH Qualifier]
- standards [MeSH Qualifier]
- supply and distribution [MeSH Qualifier]
- therapeutic use [MeSH Qualifier]
- toxicity [MeSH Qualifier]
- ultrastructure [MeSH Qualifier]
- urine [MeSH Qualifier]
Automatic exact mappings (from CISMeF team)
- E3 SUMO-Protein Ligase EGR2 [NCIt concept]
- EGR2 Gene [NCIt concept]
Record concept(s)
- early growth response protein 2 [MeSH concept]
Related MeSH Supplementary Concept(s)
- EGR2 protein, Xenopus [MeSH Supplementary Concept]
- EGR2 protein, human [MeSH Supplementary Concept]
- Egr2 protein, mouse [MeSH Supplementary Concept]
- Egr2 protein, rat [MeSH Supplementary Concept]
- Erg2b protein, zebrafish [MeSH Supplementary Concept]
See also
- charcot-marie-tooth disease [MeSH Descriptor]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Biologically Active Substance [UMLS semantic type]

Keyword's position in hierarchy(ies) :

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