Ubiquitin Carboxyl-Terminal Hydrolase 14

Preferred Label : Ubiquitin Carboxyl-Terminal Hydrolase 14;

NCIt synonyms : EC 3.4.19.12; Ubiquitin-Specific Processing Protease 14; Ubiquitin Thioesterase 14; Ubiquitin-Specific Protease 14; Ubiquitin-Specific-Processing Protease 14; Ubiquitin Thiolesterase 14; Deubiquitinating Enzyme 14; USP14;

NCIt definition : Ubiquitin carboxyl-terminal hydrolase 14 (494 aa, 56 kDa) is encoded by the human USP14 gene. This protein is involved in the regulation of both ubiquitinated protein degradation and endoplasmic reticulum-associated degradation.;

Details

Origin ID

C132092;

UMLS CUI

C1698205;

Automatic exact mappings (from CISMeF team)
- Ubiquitin-specific protease 14 [OMIM gene]
OMIM relation
- Ubiquitin-specific protease 14 [OMIM gene]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Enzyme [UMLS semantic type]
UMLS correspondences (same concept)
- USP14 protein, human [MeSH Supplementary Concept]
- USP14 protein, human [MeSH concept]
concept_is_in_subset
- CTRP Biomarker Terminology [NCIt concept]
- CTRP Molecular Genetic Biomarker Terminology [NCIt concept]
- CTRP Terminology [NCIt concept]
gene_encodes_gene_product
- Cysteine Peptidase Gene [NCIt concept]
- Enzyme Gene [NCIt concept]
- Hydrolase Gene [NCIt concept]
- Peptidase Gene [NCIt concept]
- USP14 Gene [NCIt concept]
gene_product_has_associated_anatomy
- Proteasome [NCIt concept]
gene_product_has_biochemical_function
- Ubiquitin C-Terminal Hydrolase [NCIt concept]
- Ubiquitination Regulation Protein [NCIt concept]
gene_product_has_structural_domain_or_motif
- Protease Domain [NCIt concept]
- Substrate Interaction Domain [NCIt concept]
gene_product_plays_role_in_biological_process
- Deubiquitination [NCIt concept]
- Hydrolysis [NCIt concept]
- Proteolysis [NCIt concept]
- Regulation of Proteolysis [NCIt concept]
- Ubiquitinated Protein Degradation [NCIt concept]
is_target
- USP14/UCHL5 Inhibitor VLX1570 [NCIt concept]

Keyword's position in hierarchy(ies) :

You can consult :

recommendations
documents concerning education
documents for patients