Collagenase 3 - CISMeF

Preferred Label : Collagenase 3;

NCIt synonyms : Matrix Metalloprotease 13; Collagenase-3; Matrix Metalloproteinase-13; Matrix Metalloprotease-13; Matrix Metalloproteinase 13; MMP-13; EC 3.4.24.-; MMP13;

NCIt definition : Collagenase 3 (471 aa, 54 kDa) is encoded by the human MMP13 gene. This protein plays a role in the proteolysis of the extracellular matrix.;

Details

Origin ID

C102923;

UMLS CUI

C1567335;

Automatic exact mappings (from CISMeF team)
- Matrix metalloproteinase 13 [OMIM gene]
- matrix metallopeptidase 13 [ORDO Gene]
- matrix metallopeptidase 13 [HGNC gene]
- matrix metalloproteinase 13 [MeSH Descriptor]
- matrix metalloproteinase 13 [MeSH concept]
- obsolete collagenase 3 activity [GO term]
OMIM relation
- Matrix metalloproteinase 13 [OMIM gene]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Enzyme [UMLS semantic type]
UMLS correspondences (same concept)
- MMP13 protein, human [MeSH concept]
- MMP13 protein, human [MeSH Supplementary Concept]
gene_encodes_gene_product
- Enzyme Gene [NCIt concept]
- Hydrolase Gene [NCIt concept]
- MMP13 Gene [NCIt concept]
- Metallopeptidase Gene [NCIt concept]
- Peptidase Gene [NCIt concept]
gene_product_has_associated_anatomy
- Extracellular Space [NCIt concept]
gene_product_has_biochemical_function
- Collagenase [NCIt concept]
gene_product_has_chemical_classification
- Metalloprotein [NCIt concept]
gene_product_has_structural_domain_or_motif
- Protease Domain [NCIt concept]
- Substrate Interaction Domain [NCIt concept]
gene_product_is_biomarker_type
- Metastasis and Aggressiveness Marker [NCIt concept]
gene_product_plays_role_in_biological_process
- Extracellular Matrix Degradation [NCIt concept]
- Hydrolysis [NCIt concept]
- Metal Ion Binding [NCIt concept]
- Proteolysis [NCIt concept]

Keyword's position in hierarchy(ies) :

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