Flavin-Containing Monooxygenase 1

Preferred Label : Flavin-Containing Monooxygenase 1;

NCIt synonyms : Flavin Containing Monooxygenase 1; Dimethylaniline Monooxygenase [N-Oxide-Forming] 1; FMO 1; FMO1; Dimethylaniline Oxidase 1; EC 1.14.13.148; EC 1.14.13.8; Trimethylamine Monooxygenase; Fetal Hepatic Flavin-Containing Monooxygenase 1; Flavin Containing Dimethylaniline Monoxygenase 1; Flavin-Containing Dimethylaniline Monooxygenase 1;

NCIt definition : Flavin-containing monooxygenase 1 (532 aa, 60 kDa) is encoded by the human FMO1 gene. This protein is involved in oxidation of amino-trimethylamine and a number of drugs, pesticides and xenobiotics in the fetal and adult liver.;

NCI Metathesaurus CUI : CL1907581;

Details

Origin ID

C200578;

OMIM relation
- Flavin-containing dimethylaniline monooxygenase 1 [OMIM gene]
concept_is_in_subset
- CTRP Biomarker Terminology [NCIt concept]
- CTRP Molecular Genetic Biomarker Terminology [NCIt concept]
- CTRP Terminology [NCIt concept]
gene_encodes_gene_product
- Enzyme Gene [NCIt concept]
- FMO1 Gene [NCIt concept]
- Oxidoreductase Gene [NCIt concept]
gene_product_expressed_in_tissue
- Fetal Liver [NCIt concept]
- Hepatic Tissue [NCIt concept]
gene_product_has_associated_anatomy
- Membrane of the Endoplasmic Reticulum [NCIt concept]
gene_product_has_structural_domain_or_motif
- Substrate Interaction Domain [NCIt concept]
gene_product_is_element_in_pathway
- Drug Metabolism by Cytochrome P450 Pathway [NCIt concept]
- Taurine and Hypotaurine Metabolism Pathway [NCIt concept]
gene_product_plays_role_in_biological_process
- Drug Metabolism Induction [NCIt concept]
- Oxidation [NCIt concept]
- Oxidation/Reduction [NCIt concept]
- Xenobiotic Metabolism [NCIt concept]

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