Lactosylceramide 1,3-N-Acetyl-Beta-D-Glucosaminyltransferase

Preferred Label : Lactosylceramide 1,3-N-Acetyl-Beta-D-Glucosaminyltransferase;

NCIt synonyms : LacCer Synthase; B3GN-T5; B3GNT5; Lc3 Synthase; Beta-1,3-N-Acetylglucosaminyltransferase BGnT-5; EC 2.4.1.206; beta3Gn-T5; UDP-GlcNAc:BetaGal Beta-1,3-N-Acetylglucosaminyltransferase 5; Beta-1,3-N-Acetylglucosaminyltransferase 5; Lc(3)Cer Synthase; BGnT-5; Lactotriaosylceramide Synthase; Beta-1,3-Gn-T5; UDP-GlcNAc:Beta-Gal Beta-1,3-N-Acetylglucosaminyltransferase 5; Beta 1,3 N-Acetyglucosaminyltransferase Lc3 Synthase;

NCIt definition : Lactosylceramide 1,3-N-acetyl-beta-D-glucosaminyltransferase (378 aa, 44 kDa) is encoded by the human B3GNT5 gene. This protein is involved in the synthesis of lacto- or neolacto-series carbohydrate chains on glycolipids.;

NCIt note : Lactosylceramide 1,3-N-acetyl-beta-D-glucosaminyltransferase is essential for the expression of Lewis X epitopes on glycolipids. (EntrezGene);

NCI Metathesaurus CUI : CL1787148;

Details

Origin ID

C185034;

UMLS CUI

C5565420;

Automatic exact mappings (from CISMeF team)
- Beta-1,3-n-acetylglucosaminyltransferase 5 [OMIM gene]
- Lactosylceramide 1,3-N-acetyl-beta-D-glucosaminyl-transferase (substance) [SNOMED CT concept]
- UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 5 [HGNC gene]
- lactosylceramide 1,3-N-acetyl-beta-D-glucosaminyltransferase [MeSH concept]
- lactosylceramide 1,3-N-acetyl-beta-D-glucosaminyltransferase [MeSH Supplementary Concept]
OMIM relation
- Beta-1,3-n-acetylglucosaminyltransferase 5 [OMIM gene]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Enzyme [UMLS semantic type]
UMLS correspondences (same concept)
- B3GNT5 protein, human [MeSH Supplementary Concept]
gene_encodes_gene_product
- B3GNT5 Gene [NCIt concept]
- Enzyme Gene [NCIt concept]
- Glycosyltransferase Gene [NCIt concept]
- Transferase Gene [NCIt concept]
gene_product_has_associated_anatomy
- Membrane of the Golgi Apparatus [NCIt concept]
gene_product_has_chemical_classification
- Transmembrane Protein [NCIt concept]
gene_product_has_structural_domain_or_motif
- Substrate Interaction Domain [NCIt concept]
- Transmembrane Domain [NCIt concept]
gene_product_is_element_in_pathway
- Blood Group Glycolipid Biosynthesis - Lacto and Neolacto Series Pathway [NCIt concept]
gene_product_plays_role_in_biological_process
- Biosynthetic Process [NCIt concept]
- Carbohydrate Metabolic Process [NCIt concept]
- Glycosylation [NCIt concept]
- Lipid Metabolic Process [NCIt concept]
- Protein Glycosylation [NCIt concept]

Keyword's position in hierarchy(ies) :

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