E3 Ubiquitin-Protein Ligase FANCL

Preferred Label : E3 Ubiquitin-Protein Ligase FANCL;

NCIt synonyms : Fanconi Anemia-Associated Polypeptide of 43 kDa; Fanconi Anemia-Associated Polypeptide, 43 kD; Fanconi Anemia Group L Protein; FAAP43; PHD Finger Protein 9; EC 6.3.2.-, Formerly; FANCL; EC 2.3.2.27;

NCIt definition : E3 ubiquitin-protein ligase FANCL (375 aa, 43 kDa) is encoded by the human FANCL gene. This protein is involved in the regulation of both protein ubiquitination and DNA repair.;

Details

Origin ID

C92483;

UMLS CUI

C1313279;

OMIM relation
- Fancl gene [OMIM gene]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Enzyme [UMLS semantic type]
UMLS correspondences (same concept)
- FANCL protein, human [MeSH concept]
- FANCL protein, human [MeSH Supplementary Concept]
concept_is_in_subset
- CTRP Biomarker Terminology [NCIt concept]
- CTRP Molecular Genetic Biomarker Terminology [NCIt concept]
- CTRP Terminology [NCIt concept]
gene_encodes_gene_product
- DNA Repair Gene [NCIt concept]
- Enzyme Gene [NCIt concept]
- FANCL Gene [NCIt concept]
- Transferase Gene [NCIt concept]
- Ubiquitin-Transferase Gene [NCIt concept]
gene_product_has_biochemical_function
- Fanconi Anemia Complementation Group Protein [NCIt concept]
- Ubiquitination Regulation Protein [NCIt concept]
gene_product_has_structural_domain_or_motif
- Substrate Interaction Domain [NCIt concept]
gene_product_is_element_in_pathway
- BARD1 Signaling Pathway [NCIt concept]
- Ubiquitin-mediated Proteolysis Pathway [NCIt concept]
gene_product_is_physical_part_of
- Ubiquitin Protein Ligase [NCIt concept]
gene_product_malfunction_associated_with_disease
- Fanconi Anemia [NCIt concept]
gene_product_plays_role_in_biological_process
- Cell Cycle Regulation Process [NCIt concept]
- DNA Repair [NCIt concept]
- Ubiquitinated Protein Degradation [NCIt concept]
- Ubiquitination [NCIt concept]

Keyword's position in hierarchy(ies) :

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