NCIt definition : An autosomal recessive genetic disorder characterized by bone marrow failure, skeletal
abnormalities, and an increased incidence of the development of neoplasias.;
Alternative definition : NICHD: A chromosomal instability syndrome that is the most common form of inherited
aplastic anemia. It is inherited as an autosomal recessive or X-linked disorder. In
addition to bone marrow failure, it is associated with skeletal abnormalities and
increased incidence of the development of malignancy. Multiple genes are responsible
for Fanconi anemia.; NCI-GLOSS: A rare inherited disorder in which the bone marrow does not make blood
cells. It is usually diagnosed in children between 2 and 15 years old. Symptoms include
frequent infections, easy bleeding, and extreme tiredness. People with Fanconi anemia
may have a small skeleton and brown spots on the skin. They also have an increased
risk of developing certain types of cancer.;