Glutathione Peroxidase 1

Preferred Label : Glutathione Peroxidase 1;

NCIt synonyms : Cellular Glutathione Peroxidase; GPx-1; GPX1 Protein; GSHPx-1; GPX1; EC 1.11.1.9;

NCIt definition : Glutathione peroxidase 1 (203 aa, 22 kDa) is encoded by the human GPX1 gene. This protein plays a role in glutathione metabolism, peroxide reduction and hemoglobin homeostasis.;

Details

Origin ID

C60309;

UMLS CUI

C1568555;

OMIM relation
- Glutathione peroxidase 1 [OMIM gene]
See also inter- (CISMeF)
- glutathione peroxidase 1 [HGNC gene]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Enzyme [UMLS semantic type]
UMLS correspondences (same concept)
- GPX1 protein, human [MeSH concept]
- GPX1 protein, human [MeSH Supplementary Concept]
Validated automatic mappings to NTBT
- glutathione peroxidase [MeSH Descriptor]
gene_encodes_gene_product
- Enzyme Gene [NCIt concept]
- GPX1 Gene [NCIt concept]
- Oxidoreductase Gene [NCIt concept]
gene_product_has_associated_anatomy
- Cytoplasm [NCIt concept]
gene_product_has_organism_source
- Human [NCIt concept]
gene_product_has_structural_domain_or_motif
- Substrate Interaction Domain [NCIt concept]
gene_product_is_element_in_pathway
- Amyotrophic Lateral Sclerosis Pathway [NCIt concept]
- Arachidonic Acid Metabolism Pathway [NCIt concept]
- Flumazenil Cardioprotection Pathway [NCIt concept]
- Glutathione Metabolism Pathway [NCIt concept]
- Huntington's Disease Pathway [NCIt concept]
- p53 Effector Pathway [NCIt concept]
gene_product_malfunction_associated_with_disease
- Hemolytic Anemia [NCIt concept]
gene_product_plays_role_in_biological_process
- Detoxification [NCIt concept]
- Oxidation [NCIt concept]
- Oxidation/Reduction [NCIt concept]
- Oxidative Stress [NCIt concept]

Keyword's position in hierarchy(ies) :

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