Bifunctional Purine Biosynthesis Protein PURH

Preferred Label : Bifunctional Purine Biosynthesis Protein PURH;

NCIt synonyms : IMP Synthase; IMP Cyclohydrolase; Phosphoribosylaminoimidazolecarboxamide Formyltransferase; AICAR Transformylase; 5-Aminoimidazole-4-Carboxamide Ribonucleotide Formyltransferase; Inosinicase; EC 2.1.2.3; EC 3.5.4.10; ATIC;

NCIt definition : Bifunctional purine biosynthesis protein PURH (592 aa, 65 kDa) is encoded by the human ATIC gene. This protein plays a role in the mediation of purine biosynthesis.;

NCIt note : Bifunctional purine biosynthesis protein PURH has both formyltransferase and IMP cyclohydrolase activity. (UniProt);

Details

Origin ID

C97402;

UMLS CUI

C0676764;

Automatic exact mappings (from CISMeF team)
- 5-aminoimidazole-4-carboxamide ribonucleotide formyltransferase/IMP cyclohydrolase [ORDO Gene]
- 5-aminoimidazole-4-carboxamide ribonucleotide formyltransferase/imp cyclohydrolase [OMIM gene]
- IMP cyclohydrolase [MeSH concept]
- IMP cyclohydrolase [MeSH Supplementary Concept]
- Inosine monophosphate cyclohydrolase (substance) [SNOMED CT concept]
- Phosphoribosylaminoimidazolecarboxamide formyltransferase (substance) [SNOMED CT concept]
- imp cyclohydrolase [SNOMED Notion]
- inosine monophosphate synthase [MeSH Supplementary Concept]
- phosphoribosylaminoimidazolecarboxamide formyltransferase [MeSH Descriptor]
- phosphoribosylaminoimidazolecarboxamide formyltransferase [MeSH concept]
- phosphoribosylaminoimidazolecarboxamide formyltransferase [SNOMED Notion]
OMIM relation
- 5-aminoimidazole-4-carboxamide ribonucleotide formyltransferase/imp cyclohydrolase [OMIM gene]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Enzyme [UMLS semantic type]
UMLS correspondences (same concept)
- ATIC protein, human [MeSH concept]
- Phosphoribosylaminoimidazolecarboxamide formyltransferase (substance) [SNOMED CT concept]
- phosphoribosylaminoimidazolecarboxamide formyltransferase [SNOMED Notion]
- phosphoribosylaminoimidazolecarboxamide formyltransferase [MeSH concept]
- phosphoribosylaminoimidazolecarboxamide formyltransferase [MeSH Descriptor]
concept_is_in_subset
- CTRP Biomarker Terminology [NCIt concept]
- CTRP Molecular Genetic Biomarker Terminology [NCIt concept]
- CTRP Terminology [NCIt concept]
gene_encodes_gene_product
- ATIC Gene [NCIt concept]
- Enzyme Gene [NCIt concept]
- Hydrolase Gene [NCIt concept]
- Transferase Gene [NCIt concept]
gene_product_has_associated_anatomy
- Cytosol [NCIt concept]
gene_product_has_structural_domain_or_motif
- Substrate Interaction Domain [NCIt concept]
gene_product_is_element_in_pathway
- One Carbon Pool by Folate Pathway [NCIt concept]
- Purine Metabolism Pathway [NCIt concept]
gene_product_plays_role_in_biological_process
- Hydrolysis [NCIt concept]
- Nucleotide Biosynthesis Process [NCIt concept]

Keyword's position in hierarchy(ies) :

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